N⁶-Methyl-N⁶-(4-trifluoromethyl-benzyl)-pyrido[3,2-d]pyrimidine-2,4,6-triamine

Base Information

Chemical Name:N⁶-Methyl-N⁶-(4-trifluoromethyl-benzyl)-pyrido[3,2-d]pyrimidine-2,4,6-triamine
CAS No.:93683-98-8
Molecular Formula:C₁₆H₁₅F₃N₆
Molecular Weight:348.331
Hs Code.:

N<sup>6</sup>-Methyl-N<sup>6</sup>-(4-trifluoromethyl-benzyl)-pyrido[3,2-d]pyrimidine-2,4,6-triamine

Synonyms:N⁶-Methyl-N⁶-(4-trifluoromethyl-benzyl)-pyrido[3,2-d]pyrimidine-2,4,6-triamine

Suppliers and Price of N⁶-Methyl-N⁶-(4-trifluoromethyl-benzyl)-pyrido[3,2-d]pyrimidine-2,4,6-triamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N⁶-Methyl-N⁶-(4-trifluoromethyl-benzyl)-pyrido[3,2-d]pyrimidine-2,4,6-triamine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N⁶-Methyl-N⁶-(4-trifluoromethyl-benzyl)-pyrido[3,2-d]pyrimidine-2,4,6-triamine

There total 4 articles about N⁶-Methyl-N⁶-(4-trifluoromethyl-benzyl)-pyrido[3,2-d]pyrimidine-2,4,6-triamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

: 29671-92-9
chloroformamidine hydrochloride

: 93683-86-4
3-Amino-6-[methyl-(4-trifluoromethyl-benzyl)-amino]-pyridine-2-carbonitrile

: 93683-98-8
N⁶-Methyl-N⁶-(4-trifluoromethyl-benzyl)-pyrido[3,2-d]pyrimidine-2,4,6-triamine

Guidance literature:: In dimethyl sulfoxide; at 150 - 155 ℃; for 1h;
DOI:10.1021/jm00380a018

Reference yield:

: 93683-65-9
6-chloro-3-nitropicolinonitrile

: 93683-98-8
N⁶-Methyl-N⁶-(4-trifluoromethyl-benzyl)-pyrido[3,2-d]pyrimidine-2,4,6-triamine

Guidance literature:: Multi-step reaction with 3 steps

1: 68 percent / Et₃N / 2-ethoxy-ethanol / 1 h / Heating

2: 67 percent / Fe, conc. aq. HCl / 1 h / Heating

3: 53 percent / dimethylsulfoxide / 1 h / 150 - 155 °C

With hydrogenchloride; iron; triethylamine; In 2-ethoxy-ethanol; dimethyl sulfoxide;
DOI:10.1021/jm00380a018

Reference yield:

: 90390-11-7
N-Methyl-4-(trifluoromethyl)benzylamine

: 93683-98-8
N⁶-Methyl-N⁶-(4-trifluoromethyl-benzyl)-pyrido[3,2-d]pyrimidine-2,4,6-triamine

Guidance literature:: Multi-step reaction with 3 steps

1: 68 percent / Et₃N / 2-ethoxy-ethanol / 1 h / Heating

2: 67 percent / Fe, conc. aq. HCl / 1 h / Heating

3: 53 percent / dimethylsulfoxide / 1 h / 150 - 155 °C

With hydrogenchloride; iron; triethylamine; In 2-ethoxy-ethanol; dimethyl sulfoxide;
DOI:10.1021/jm00380a018