N-benzyloxypiperidine

Base Information

• Chemical Name: N-benzyloxypiperidine
• CAS No.: 46346-67-2
• Molecular Formula: C₁₂H₁₇NO
• Molecular Weight: 191.273

Synonyms:N-benzyloxypiperidine

Chemical Property of N-benzyloxypiperidine

Chemical Property:

Purity/Quality:

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• Pictogram(s):  
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Technology Process of N-benzyloxypiperidine

There total 2 articles about N-benzyloxypiperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

N-benzylpiperidine N-oxide (29872-25-1) → N-benzyloxypiperidine (46346-67-2)

Guidance literature:

In toluene; for 4h; Heating;

DOI:10.1016/S0022-328X(00)81383-2

Reference yield:

→ N-benzyloxypiperidine (46346-67-2)

Guidance literature:

Aethoxyimid 24, LiAlH4;

DOI:10.1016/S0040-4020(01)93077-7

Reference yield: 91.0%

N-benzyloxypiperidine (46346-67-2) + Diphenylphosphine oxide (4559-70-0) → diphenyl(piperidin-1-yl)phosphine oxide (6230-68-8)

Guidance literature:

With potassium carbonate; In tert-Amyl alcohol; at 105 ℃; for 8h;

DOI:10.1021/acs.orglett.5b03056

upstream raw materials:

N-benzylpiperidine N-oxide

Downstream raw materials:

piperidine

N-Formylpiperidine

benzaldehyde

N-Benzylpiperidine

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