N'-diphenylmethylenebenzohydrazide

Base Information

• Chemical Name: N'-diphenylmethylenebenzohydrazide
• CAS No.: 7355-77-3
• Molecular Formula: C20H16N2O
• Molecular Weight: 300.36
• NSC Number: 58891
• DSSTox Substance ID: DTXSID50994324
• Mol file: 7355-77-3.mol

Synonyms:7355-77-3;NSC58891;benzophenone N-benzoylhydrazone;SCHEMBL1562723;DTXSID50994324;N'-diphenylmethylenebenzohydrazide;DVRPCCKVVMFGSD-UHFFFAOYSA-N;NSC-58891;AKOS000936447;N-(Diphenylmethylidene)benzenecarbohydrazonic acid

Chemical Property of N'-diphenylmethylenebenzohydrazide

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: 1.08g/cm³
• XLogP3: 4.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 300.126263138
• Heavy Atom Count: 23
• Complexity: 380

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=NNC(=O)C2=CC=CC=C2)C3=CC=CC=C3

Technology Process of N'-diphenylmethylenebenzohydrazide

There total 11 articles about N'-diphenylmethylenebenzohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

benzophenone (119-61-9) + benzoic acid hydrazide (613-94-5) → N-benzoyl benzophenone hydrazone (7355-77-3)

Guidance literature:

With cerium(III) chloride heptahydrate; In ethanol; at 70 ℃; for 24h; diastereoselective reaction; Green chemistry;

DOI:10.1002/ejoc.201402609

Reference yield:

benzhydryl-benzoyl-diazene (89449-70-7) → N-benzoyl benzophenone hydrazone (7355-77-3)

Guidance literature:

With toluene; at 100 ℃;

Reference yield:

benzoic acid ethyl ester (93-89-0,99341-95-4) → N-benzoyl benzophenone hydrazone (7355-77-3)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrazine hydrate

With hydrazine hydrate;

DOI:10.1039/P19810000349

upstream raw materials:

benzhydryl-benzoyl-diazene

benzophenone

benzoic acid hydrazide

N-(diphenylmethylidene)phenylamine

Downstream raw materials:

benzophenone

benzoic acid hydrazide

N'-(1,1-diphenylbut-3-en-1-yl)benzohydrazide

Diphenylmethane

Refernces

• 1、 Dos Santos Filho, José Maurício. "Mild, Stereoselective, and Highly Efficient Synthesis of N-Acylhydrazones Mediated by CeCl3·7H2O in a Broad Range of Solvents". supporting information. p. 6411 - 6417. Retrieved 2016/02/18.
• 2、 Flowers, William T.,Robinson, John F.,Taylor, David R.,Tipping, Anthony E.. "Unsaturated Compounds containing Nitrogen. Part 4. Further Reactions of 1-Chloro-2,3-diazabutadienes with S-Nucleophiles". . p. 349 - 355. Retrieved 2007/10/02.