5-(4-fluorobenzoyl)-1-methyl-6-phenyl-1,2-dihydropyridine-3,3(4H)-dicarbonitrile

Base Information

Chemical Name:5-(4-fluorobenzoyl)-1-methyl-6-phenyl-1,2-dihydropyridine-3,3(4H)-dicarbonitrile
CAS No.:1261271-03-7
Molecular Formula:C₂₁H₁₆FN₃O
Molecular Weight:345.376
Hs Code.:

Synonyms:5-(4-fluorobenzoyl)-1-methyl-6-phenyl-1,2-dihydropyridine-3,3(4H)-dicarbonitrile

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-(4-fluorobenzoyl)-1-methyl-6-phenyl-1,2-dihydropyridine-3,3(4H)-dicarbonitrile

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Technology Process of 5-(4-fluorobenzoyl)-1-methyl-6-phenyl-1,2-dihydropyridine-3,3(4H)-dicarbonitrile

There total 1 articles about 5-(4-fluorobenzoyl)-1-methyl-6-phenyl-1,2-dihydropyridine-3,3(4H)-dicarbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 82677-84-7
1-(4-fluorophenyl)-3-phenylprop-2-yn-1-one

: 74-89-5
methylamine

: 109-77-3
malononitrile

: 1261271-03-7
5-(4-fluorobenzoyl)-1-methyl-6-phenyl-1,2-dihydropyridine-3,3(4H)-dicarbonitrile

Guidance literature:: 1-(4-fluorophenyl)-3-phenylprop-2-yn-1-one; methylamine; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h;

formaldehyd; malononitrile; With L-proline; In N,N-dimethyl-formamide; at 100 ℃; for 12h;
DOI:10.1016/j.tet.2010.10.041