N-Benzyl-N,α,α,α-tetramethylsilanamine

Base Information

• Chemical Name: N-Benzyl-N,α,α,α-tetramethylsilanamine
• CAS No.: 14884-70-9
• Molecular Formula: C11H19 N Si
• Molecular Weight: 193.364
• Hs Code.: 2931900090
• Mol file: 14884-70-9.mol

Synonyms:Silylamine,N-benzyl-N,1,1,1-tetramethyl- (8CI); (Methylbenzylamino)trimethylsilane

Chemical Property of N-Benzyl-N,α,α,α-tetramethylsilanamine

Chemical Property:

• Vapor Pressure: 0.114mmHg at 25°C
• Boiling Point: 227.8°Cat760mmHg
• Flash Point: 91.6°C
• PSA: 3.24000
• Density: 0.9g/cm³
• LogP: 2.95330

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-Benzyl-N,α,α,α-tetramethylsilanamine

There total 4 articles about N-Benzyl-N,α,α,α-tetramethylsilanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

chloro-trimethyl-silane (75-77-4) + benzyl-methyl-amine (103-67-3) → N-Methyl-N-(trimethylsilyl)benzylamin (14884-70-9)

Guidance literature:

benzyl-methyl-amine; With n-butyllithium; In diethyl ether; hexane; at -78 - -60 ℃; for 1h; Inert atmosphere;

chloro-trimethyl-silane; In diethyl ether; hexane; at -70 - 20 ℃; Inert atmosphere;

Reference yield:

trimethylsilyl trifluoromethanesulfonate (27607-77-8) + benzyl-methyl-amine (103-67-3) → N-Methyl-N-(trimethylsilyl)benzylamin (14884-70-9)

Guidance literature:

With N,N,N',N'-tetramethyl-1,8-diaminonaphthalene; In dichloromethane; at 0 - 20 ℃; for 0.5h; Schlenk technique; Inert atmosphere;

DOI:10.1021/jo501644m

Reference yield:

N,O-bis-(trimethylsilyl)-acetamide (10416-59-8) + benzyl-methyl-amine (103-67-3) → N-Methyl-N-(trimethylsilyl)benzylamin (14884-70-9)

Guidance literature:

In acetonitrile; Heating;

DOI:10.1021/jo01287a040

upstream raw materials:

N-methyl-α-(trimethylsilyl)benzylamine

chloro-trimethyl-silane

benzyl-methyl-amine

N,O-bis-(trimethylsilyl)-acetamide

Downstream raw materials:

1-(N-methyl-N-benzyl)amino-6-methyl-1,3-dihydrofuro[3,4-c]pyridin-7-ol

chloro-trimethyl-silane

N,N'-Dibenzyl-N,N'-dimethylsulfinyldiamin

Refernces

• 1、 -. "DISUBSTITUTED-AMINODIFLUOROSULFINIUM SALTS, PROCESS FOR PREPARING SAME AND METHOD OF USE AS DEOXOFLUORINATION REAGENTS". Page/Page column 29-30. . Retrieved 2010/12/31.