1-(chloromethyl)-4-methoxy-2-nitrobenzene

Base Information Edit

Chemical Name:1-(chloromethyl)-4-methoxy-2-nitrobenzene
CAS No.:101080-02-8
Molecular Formula:C₈H₈ClNO₃
Molecular Weight:201.609
Hs Code.:
Mol file:101080-02-8.mol

Synonyms:1-(chloromethyl)-4-methoxy-2-nitrobenzene

Suppliers and Price of 1-(chloromethyl)-4-methoxy-2-nitrobenzene

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Alichem
4-Methoxy-2-nitrobenzylchloride
1g
$ 1579.40

Alichem
4-Methoxy-2-nitrobenzylchloride
500mg
$ 855.75

Alichem
4-Methoxy-2-nitrobenzylchloride
250mg
$ 489.60

Total 1 raw suppliers

Chemical Property of 1-(chloromethyl)-4-methoxy-2-nitrobenzene Edit

Chemical Property:

Purity/Quality:

95% ^*data from raw suppliers

4-Methoxy-2-nitrobenzylchloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-(chloromethyl)-4-methoxy-2-nitrobenzene

There total 7 articles about 1-(chloromethyl)-4-methoxy-2-nitrobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 75-09-2
dichloromethane

: 555-03-3
3-nitroanisole

: 101080-02-8
1-(chloromethyl)-4-methoxy-2-nitrobenzene

Guidance literature:: dichloromethane; With n-butyllithium; In tetrahydrofuran; hexane; at -100 ℃; for 0.333333h; Inert atmosphere;

3-nitroanisole; With N,N,N,N,-tetramethylethylenediamine; In tetrahydrofuran; hexane; at -100 ℃; for 24h; Inert atmosphere;

With ammonium chloride; In tetrahydrofuran; hexane; water; at -100 - 20 ℃; Inert atmosphere;
DOI:10.1021/acs.orglett.9b01676

Reference yield:

: 22996-23-2
(4-methoxy-2-nitro-phenyl)-methanol

: 101080-02-8
1-(chloromethyl)-4-methoxy-2-nitrobenzene

Guidance literature:: With phosphorus pentachloride; In chloroform; at 20 ℃; for 1h;

Reference yield:

: 187731-64-2
acetic acid 4-methoxy-2-nitro-benzyl ester

: 101080-02-8
1-(chloromethyl)-4-methoxy-2-nitrobenzene

Guidance literature:: Multi-step reaction with 2 steps

1: sodium methylate / methanol / 3 h / 20 °C

2: phosphorus pentachloride / chloroform / 1 h / 20 °C

With phosphorus pentachloride; sodium methylate; In methanol; chloroform;