4'-tert-butyldimethylsilyldaidzein

Base Information

• Chemical Name: 4'-tert-butyldimethylsilyldaidzein
• CAS No.: 606125-89-7
• Molecular Formula: C₂₁H₂₄O₄Si
• Molecular Weight: 368.505
• Mol file: 606125-89-7.mol

Synonyms:4'-tert-butyldimethylsilyldaidzein

Chemical Property of 4'-tert-butyldimethylsilyldaidzein

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 4'-tert-butyldimethylsilyldaidzein

There total 1 articles about 4'-tert-butyldimethylsilyldaidzein which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

daidzein (486-66-8) + tert-butyldimethylsilyl chloride (18162-48-6) → 4'-tert-butyldimethylsilyldaidzein (606125-89-7)

Guidance literature:

With potassium tert-butylate; In N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1016/S0040-4020(03)00869-X

Reference yield:

4'-tert-butyldimethylsilyldaidzein (606125-89-7) → sulfuric acid mono-{3-[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-4-oxo-4H-chromen-7-yl} ester

Guidance literature:

With pyridine; chlorosulfonic acid; at 0 - 20 ℃;

DOI:10.1016/S0040-4020(03)00869-X

Reference yield:

4'-tert-butyldimethylsilyldaidzein (606125-89-7) → daidzein‐7‐sulfate

Guidance literature:

Multi-step reaction with 2 steps

1: ClSO₃H; pyridine / 0 - 20 °C

2: TBAF; aq. K₂CO₃ / tetrahydrofuran; methanol / 2 h / pH 10

With pyridine; chlorosulfonic acid; tetrabutyl ammonium fluoride; potassium carbonate; In tetrahydrofuran; methanol;

DOI:10.1016/S0040-4020(03)00869-X

upstream raw materials:

daidzein

tert-butyldimethylsilyl chloride