C₂HF₃O₂*C₁₁H₁₅NO₂

Base Information

• Chemical Name: C₂HF₃O₂*C₁₁H₁₅NO₂
• CAS No.: 1290070-54-0
• Molecular Formula: C₂HF₃O₂*C₁₁H₁₅NO₂
• Molecular Weight: 307.27
• Mol file: 1290070-54-0.mol

Synonyms:C₂HF₃O₂*C₁₁H₁₅NO₂

Chemical Property of C₂HF₃O₂*C₁₁H₁₅NO₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂HF₃O₂*C₁₁H₁₅NO₂

There total 3 articles about C₂HF₃O₂*C₁₁H₁₅NO₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 4-[[(1,1-dimethylethoxy)carbonyl]methylamino]butanoic acid (133171-74-1) → C2HF3O2*C11H15NO2 (1290070-54-0)

Guidance literature:

Multi-step reaction with 3 steps

1.1: lithium hydroxide / tetrahydrofuran; water / Inert atmosphere

1.2: Inert atmosphere

2.1: dmap; dicyclohexyl-carbodiimide / dichloromethane / 1 h / Inert atmosphere

3.1: dichloromethane / 2 h / Inert atmosphere

With dmap; dicyclohexyl-carbodiimide; lithium hydroxide; In tetrahydrofuran; dichloromethane; water;

DOI:10.1039/c0ob00890g

Reference yield:

4-[(tert-butoxycarbonyl)(methyl)amino]butanoic acid (94994-39-5) + phenol (108-95-2,27073-41-2) → C2HF3O2*C11H15NO2 (1290070-54-0)

Guidance literature:

Multi-step reaction with 2 steps

1: dmap; dicyclohexyl-carbodiimide / dichloromethane / 1 h / Inert atmosphere

2: dichloromethane / 2 h / Inert atmosphere

With dmap; dicyclohexyl-carbodiimide; In dichloromethane;

DOI:10.1039/c0ob00890g

Reference yield:

C16H23NO4 (1290070-21-1) + trifluoroacetic acid (76-05-1) → C2HF3O2*C11H15NO2 (1290070-54-0)

Guidance literature:

In dichloromethane; for 2h; Inert atmosphere;

DOI:10.1039/c0ob00890g

upstream raw materials:

C₁₆H₂₃NO₄

trifluoroacetic acid

4-[(tert-butoxycarbonyl)(methyl)amino]butanoic acid

phenol

Downstream raw materials:

1-methyl-pyrrolidin-2-one

Refernces