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4,4'-Diacetamidodiphenylmethane

Base Information Edit
  • Chemical Name:4,4'-Diacetamidodiphenylmethane
  • CAS No.:2719-05-3
  • Molecular Formula:C17H18 N2 O2
  • Molecular Weight:282.342
  • Hs Code.:
  • European Community (EC) Number:665-398-6
  • NSC Number:12407
  • UNII:U2D9UMX8Z2
  • DSSTox Substance ID:DTXSID40872849
  • Nikkaji Number:J1.957.136J
  • Wikidata:Q81978510
  • ChEMBL ID:CHEMBL478306
  • Mol file:2719-05-3.mol
4,4'-Diacetamidodiphenylmethane

Synonyms:2719-05-3;4,4'-Diacetamidodiphenylmethane;FH1;N,N'-(Methylenebis(4,1-phenylene))diacetamide;FH1(BRD-K4477);FH 1;NSC 12407;N-[4-[(4-acetamidophenyl)methyl]phenyl]acetamide;Acetamide, N,N'-(methylenedi-4,1-phenylene)bis-;N,N'-Diacetyl-4,4'-diaminodiphenylmethane;N,N'-(4,4'-methylenebis(4,1-phenylene))diacetamide;Bis(4-acetamidophenyl)methane;Methylenebis-4,4'-acetanilide;Acetanilide, 4',4'''-methylenebis-;U2D9UMX8Z2;BRD-K4477;NSC-12407;N-{4-[(4-Acetamidophenyl)methyl]phenyl}acetamide;CCRIS 5692;NSC12407;N,N'-AcetylMDA;Maybridge4_002841;UNII-U2D9UMX8Z2;N,4'-diaminodiphenylmethane;N,N'-(methylenedi-4,1-phenylene)bis(acetamide);p,p'-Methylenebisacetanilide;Oprea1_225761;SCHEMBL274924;CHEMBL478306;FH-1;Acetanilide,4'''-methylenebis-;BRD K4477;BRD4477;DTXSID40872849;HMS1529B03;HMS3653F05;BCP09483;BRD-4477;EX-A1971;HB3565;MFCD00027653;s7450;AKOS002813448;AM85691;CCG-267267;CS-3330;NCGC00176495-01;AC-33028;AS-16810;HY-12346;4',4''-METHYLENEBIS(ACETANILIDE);N-[4-(4-Acetamidobenzyl)Phenyl]Acetamide;SW220056-1;A14153;Acetamide,N'-(methylenedi-4,1-phenylene)bis-;I11729;N,N'-(Methylenedi-4,1-phenylene)bis-acetamide;N,N'-(Methylenedi-4,1-phenylene)bis- acetamide;BRD-K44777625-001-01-9

Suppliers and Price of 4,4'-Diacetamidodiphenylmethane
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • FH1
  • 5mg
  • $ 45.00
  • DC Chemicals
  • FH1(BRD-K4477) >98%
  • 1 g
  • $ 1800.00
  • DC Chemicals
  • FH1(BRD-K4477) >98%
  • 250 mg
  • $ 950.00
  • DC Chemicals
  • FH1(BRD-K4477) >98%
  • 100 mg
  • $ 500.00
  • Crysdot
  • FH1 98+%
  • 50mg
  • $ 330.00
  • Cayman Chemical
  • BRD-K4477 ≥98%
  • 5mg
  • $ 39.00
  • Cayman Chemical
  • BRD-K4477 ≥98%
  • 25mg
  • $ 156.00
  • Cayman Chemical
  • BRD-K4477 ≥98%
  • 10mg
  • $ 70.00
  • Cayman Chemical
  • BRD-K4477 ≥98%
  • 50mg
  • $ 273.00
  • Atlantic Research Chemicals
  • 4,4''-Diacetamidodiphenylmethane 95%
  • 1gm:
  • $ 279.23
Total 15 raw suppliers
Chemical Property of 4,4'-Diacetamidodiphenylmethane Edit
Chemical Property:
  • Melting Point:227-228 °C 
  • Boiling Point:564.6°Cat760mmHg 
  • PKA:14.73±0.70(Predicted) 
  • Flash Point:217.8°C 
  • PSA:58.20000 
  • Density:1.201g/cm3 
  • LogP:3.34020 
  • Storage Temp.:2-8°C 
  • Solubility.:Soluble in DMSO (up to 30 mg/ml) 
  • XLogP3:2.5
  • Hydrogen Bond Donor Count:2
  • Hydrogen Bond Acceptor Count:2
  • Rotatable Bond Count:4
  • Exact Mass:282.136827821
  • Heavy Atom Count:21
  • Complexity:320
Purity/Quality:

98%,99%, *data from raw suppliers

FH1 *data from reagent suppliers

Safty Information:
  • Pictogram(s):
  • Hazard Codes:
  • Statements: 50/53 
  • Safety Statements: 60-61 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:CC(=O)NC1=CC=C(C=C1)CC2=CC=C(C=C2)NC(=O)C
  • Description FH-1 (2719-05-3) enhances differentiation of induced pluripotent stem cells (iPSC) to hepatocytes. Promotes the maturation of iPSC-derived hepatocytes.
  • Uses FH 1 is used as an inducer of cell proliferations (i.e. inducing proliferation and differentiation of stem cells for formation of hepatocytes for treatment of liver disease).
Technology Process of 4,4'-Diacetamidodiphenylmethane

There total 11 articles about 4,4'-Diacetamidodiphenylmethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With o-benzenedisulfonimide; isopropyl alcohol; at 80 ℃; for 8h;
DOI:10.1002/ejoc.200900444
Guidance literature:
With pyridine; dmap; In dichloromethane; at 25 ℃; for 12h; Inert atmosphere;
DOI:10.1016/j.bmcl.2010.12.132
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