Carbonic acid 4-(4-{(S)-6-allyloxycarbonylamino-2-[(S)-2-((R)-2-allyloxycarbonylamino-propionylamino)-3-phenyl-propionylamino]-hexanoylamino}-benzyloxycarbonylamino)-benzyl ester 4-nitro-phenyl ester

Base Information

• Chemical Name: Carbonic acid 4-(4-{(S)-6-allyloxycarbonylamino-2-[(S)-2-((R)-2-allyloxycarbonylamino-propionylamino)-3-phenyl-propionylamino]-hexanoylamino}-benzyloxycarbonylamino)-benzyl ester 4-nitro-phenyl ester
• CAS No.: 393521-99-8
• Molecular Formula: C₄₈H₅₃N₇O₁₄
• Molecular Weight: 951.987

Synonyms:Carbonic acid 4-(4-{(S)-6-allyloxycarbonylamino-2-[(S)-2-((R)-2-allyloxycarbonylamino-propionylamino)-3-phenyl-propionylamino]-hexanoylamino}-benzyloxycarbonylamino)-benzyl ester 4-nitro-phenyl ester

Chemical Property of Carbonic acid 4-(4-{(S)-6-allyloxycarbonylamino-2-[(S)-2-((R)-2-allyloxycarbonylamino-propionylamino)-3-phenyl-propionylamino]-hexanoylamino}-benzyloxycarbonylamino)-benzyl ester 4-nitro-phenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Carbonic acid 4-(4-{(S)-6-allyloxycarbonylamino-2-[(S)-2-((R)-2-allyloxycarbonylamino-propionylamino)-3-phenyl-propionylamino]-hexanoylamino}-benzyloxycarbonylamino)-benzyl ester 4-nitro-phenyl ester

There total 3 articles about Carbonic acid 4-(4-{(S)-6-allyloxycarbonylamino-2-[(S)-2-((R)-2-allyloxycarbonylamino-propionylamino)-3-phenyl-propionylamino]-hexanoylamino}-benzyloxycarbonylamino)-benzyl ester 4-nitro-phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

4-Nitrophenyl chloroformate (7693-46-1) + (4-Hydroxymethyl-phenyl)-carbamic acid 4-{(S)-6-allyloxycarbonylamino-2-[(S)-2-((R)-2-allyloxycarbonylamino-propionylamino)-3-phenyl-propionylamino]-hexanoylamino}-benzyl ester (393521-96-5) → Carbonic acid 4-(4-{(S)-6-allyloxycarbonylamino-2-[(S)-2-((R)-2-allyloxycarbonylamino-propionylamino)-3-phenyl-propionylamino]-hexanoylamino}-benzyloxycarbonylamino)-benzyl ester 4-nitro-phenyl ester (393521-99-8)

Guidance literature:

With pyridine; In tetrahydrofuran; dichloromethane; at 0 - 20 ℃;

DOI:10.1021/jo0158884

Reference yield:

4-aminobenzenemethanol (623-04-1) → Carbonic acid 4-(4-{(S)-6-allyloxycarbonylamino-2-[(S)-2-((R)-2-allyloxycarbonylamino-propionylamino)-3-phenyl-propionylamino]-hexanoylamino}-benzyloxycarbonylamino)-benzyl ester 4-nitro-phenyl ester (393521-99-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 97 percent / DIPEA; N-hydroxybenzotriazole / dimethylformamide / 24 h

2: 84 percent / pyridine / tetrahydrofuran; CH₂Cl₂ / 0 - 20 °C

With pyridine; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/jo0158884

Reference yield:

Aloc-D-Ala-Phe-Lys(Aloc)-p-aminobenzyl oxycarbonyl p-nitrophenyl carbonate (253863-34-2) → Carbonic acid 4-(4-{(S)-6-allyloxycarbonylamino-2-[(S)-2-((R)-2-allyloxycarbonylamino-propionylamino)-3-phenyl-propionylamino]-hexanoylamino}-benzyloxycarbonylamino)-benzyl ester 4-nitro-phenyl ester (393521-99-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 97 percent / DIPEA; N-hydroxybenzotriazole / dimethylformamide / 24 h

2: 84 percent / pyridine / tetrahydrofuran; CH₂Cl₂ / 0 - 20 °C

With pyridine; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/jo0158884

upstream raw materials:

4-Nitrophenyl chloroformate

(4-Hydroxymethyl-phenyl)-carbamic acid 4-{(S)-6-allyloxycarbonylamino-2-[(S)-2-((R)-2-allyloxycarbonylamino-propionylamino)-3-phenyl-propionylamino]-hexanoylamino}-benzyl ester

4-aminobenzenemethanol

Aloc-D-Ala-Phe-Lys(Aloc)-p-aminobenzyl oxycarbonyl p-nitrophenyl carbonate

Downstream raw materials:

C₄₉H₅₇N₇O₁₂

C₈₉H₉₉N₇O₂₅

Carbonic acid 4-[4-(4-{(S)-6-allyloxycarbonylamino-2-[(S)-2-((R)-2-allyloxycarbonylamino-propionylamino)-3-phenyl-propionylamino]-hexanoylamino}-benzyloxycarbonylamino)-benzyloxycarbonylamino]-benzyl ester 4-nitro-phenyl ester

C₆₉H₇₇N₇O₂₂

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 393521-99-8 Carbonic acid 4-(4-{(S)-6-allyloxycarbonylamino-2-[(S)-2-((R)-2-allyloxycarbonylamino-propionylamino)-3-phenyl-propionylamino]-hexanoylamino}-benzyloxycarbonylamino)-benzyl ester 4-nitro-phenyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send