2-diphenylmethylsilylethyl S-p-methoxyphenyl phosphorothioate

Base Information

• Chemical Name: 2-diphenylmethylsilylethyl S-p-methoxyphenyl phosphorothioate
• CAS No.: 73364-59-7
• Molecular Formula: C₆H₁₃N*C₂₂H₂₅O₄PSSi
• Molecular Weight: 543.739
• Mol file: 73364-59-7.mol

Synonyms:2-diphenylmethylsilylethyl S-p-methoxyphenyl phosphorothioate

Chemical Property of 2-diphenylmethylsilylethyl S-p-methoxyphenyl phosphorothioate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-diphenylmethylsilylethyl S-p-methoxyphenyl phosphorothioate

There total 3 articles about 2-diphenylmethylsilylethyl S-p-methoxyphenyl phosphorothioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diphenylmethylsilylethylethanol (40438-48-0) → 2-diphenylmethylsilylethyl S-p-methoxyphenyl phosphorothioate (73364-59-7)

Guidance literature:

Multi-step reaction with 2 steps

1: TPS / pyridine

2: H₂O, NaOH / dioxane / 0.5 h / Ambient temperature

With sodium hydroxide; water; In 1,4-dioxane; pyridine;

DOI:10.1016/S0040-4039(01)93285-X

Reference yield:

S, S'-di-p-methoxy-phenyl phosphorodithioate → 2-diphenylmethylsilylethyl S-p-methoxyphenyl phosphorothioate (73364-59-7)

Guidance literature:

Multi-step reaction with 2 steps

1: TPS / pyridine

2: H₂O, NaOH / dioxane / 0.5 h / Ambient temperature

With sodium hydroxide; water; In 1,4-dioxane; pyridine;

DOI:10.1016/S0040-4039(01)93285-X

Reference yield:

cyclohexyl-ammonium cation (29384-28-9) + Dithiophosphoric acid S,S'-bis-(4-methoxy-phenyl) ester O-[2-(methyl-diphenyl-silanyl)-ethyl] ester (73364-60-0) → 2-diphenylmethylsilylethyl S-p-methoxyphenyl phosphorothioate (73364-59-7)

Guidance literature:

With sodium hydroxide; water; In 1,4-dioxane; for 0.5h; Yield given; Ambient temperature;

DOI:10.1016/S0040-4039(01)93285-X

upstream raw materials:

cyclohexyl-ammonium cation

Dithiophosphoric acid S,S'-bis-(4-methoxy-phenyl) ester O-[2-(methyl-diphenyl-silanyl)-ethyl] ester

diphenylmethylsilylethylethanol

Downstream raw materials:

2-diphenylmethylsilylethyl S-p-methoxyphenyl 5'-O-monomethoxytritylthymidine 3'-phosphorothioate

Thiophosphoric acid O-[(2S,3R,5S)-2-hydroxymethyl-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl] ester S-(4-methoxy-phenyl) ester O'-[2-(methyl-diphenyl-silanyl)-ethyl] ester