2'-deoxy-N⁶-[(9H-fluoren-9-ylmethoxy)carbonyl]-5'-O-{[2-(4-nitrophenyl)ethoxy]carbonyl}adenosine 3'-[2-(4-nitrophenyl)ethyl diisopropylphosphoramidite]

Base Information

• Chemical Name: 2'-deoxy-N⁶-[(9H-fluoren-9-ylmethoxy)carbonyl]-5'-O-{[2-(4-nitrophenyl)ethoxy]carbonyl}adenosine 3'-[2-(4-nitrophenyl)ethyl diisopropylphosphoramidite]
• CAS No.: 663918-67-0
• Molecular Formula: C₄₈H₅₁N₈O₁₂P
• Molecular Weight: 962.953

Synonyms:2'-deoxy-N⁶-[(9H-fluoren-9-ylmethoxy)carbonyl]-5'-O-{[2-(4-nitrophenyl)ethoxy]carbonyl}adenosine 3'-[2-(4-nitrophenyl)ethyl diisopropylphosphoramidite]

Chemical Property of 2'-deoxy-N⁶-[(9H-fluoren-9-ylmethoxy)carbonyl]-5'-O-{[2-(4-nitrophenyl)ethoxy]carbonyl}adenosine 3'-[2-(4-nitrophenyl)ethyl diisopropylphosphoramidite]

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2'-deoxy-N⁶-[(9H-fluoren-9-ylmethoxy)carbonyl]-5'-O-{[2-(4-nitrophenyl)ethoxy]carbonyl}adenosine 3'-[2-(4-nitrophenyl)ethyl diisopropylphosphoramidite]

There total 3 articles about 2'-deoxy-N⁶-[(9H-fluoren-9-ylmethoxy)carbonyl]-5'-O-{[2-(4-nitrophenyl)ethoxy]carbonyl}adenosine 3'-[2-(4-nitrophenyl)ethyl diisopropylphosphoramidite] which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

2-(4-nitrophenyl)ethyl diisopropylphosphoramidochloridite (153120-90-2) + 2'-deoxy-N6-[(9H-fluoren-9-ylmethoxy)carbonyl]-5'-O-{[2-(4-nitrophenyl)ethoxy]carbonyl}adenosine → 2'-deoxy-N6-[(9H-fluoren-9-ylmethoxy)carbonyl]-5'-O-{[2-(4-nitrophenyl)ethoxy]carbonyl}adenosine 3'-[2-(4-nitrophenyl)ethyl diisopropylphosphoramidite] (663918-67-0)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 1.16667h;

DOI:10.1002/hlca.200390186

Reference yield:

2'-deoxy-N6-[(9H-fluoren-9-ylmethoxy)carbonyl]adenosine (87424-20-2) → 2'-deoxy-N6-[(9H-fluoren-9-ylmethoxy)carbonyl]-5'-O-{[2-(4-nitrophenyl)ethoxy]carbonyl}adenosine 3'-[2-(4-nitrophenyl)ethyl diisopropylphosphoramidite] (663918-67-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 78 percent / pyridine / CH₂Cl₂ / 4 h / -30 - 20 °C

2: 60 percent / EtiPr₂N / CH₂Cl₂ / 1.17 h / 20 °C

With pyridine; N-ethyl-N,N-diisopropylamine; In dichloromethane;

DOI:10.1002/hlca.200390186

Reference yield:

2-(4-nitrophenyl)ethoxycarbonyl chloride (88091-68-3) → 2'-deoxy-N6-[(9H-fluoren-9-ylmethoxy)carbonyl]-5'-O-{[2-(4-nitrophenyl)ethoxy]carbonyl}adenosine 3'-[2-(4-nitrophenyl)ethyl diisopropylphosphoramidite] (663918-67-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 78 percent / pyridine / CH₂Cl₂ / 4 h / -30 - 20 °C

2: 60 percent / EtiPr₂N / CH₂Cl₂ / 1.17 h / 20 °C

With pyridine; N-ethyl-N,N-diisopropylamine; In dichloromethane;

DOI:10.1002/hlca.200390186

upstream raw materials:

2-(4-nitrophenyl)ethyl diisopropylphosphoramidochloridite

2'-deoxy-N⁶-[(9H-fluoren-9-ylmethoxy)carbonyl]adenosine

2-(4-nitrophenyl)ethoxycarbonyl chloride

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 663918-67-0 2'-deoxy-N⁶-[(9H-fluoren-9-ylmethoxy)carbonyl]-5'-O-{[2-(4-nitrophenyl)ethoxy]carbonyl}adenosine 3'-[2-(4-nitrophenyl)ethyl diisopropylphosphoramidite]

Send

Send

Metric Ton KG G Pound L ML

Send

Send