Scopine

Base Information Edit

Chemical Name:Scopine
CAS No.:498-45-3
Molecular Formula:C8H13NO2
Molecular Weight:155.197
Hs Code.:29349990
UNII:Z5LGM3Q28U
DSSTox Substance ID:DTXSID801030466,DTXSID301151677
Nikkaji Number:J404.695A,J306.683E
Wikipedia:Scopine
Wikidata:Q76120007,Q7434451
ChEMBL ID:CHEMBL4303435,CHEMBL4303536
Mol file:498-45-3.mol

Synonyms:Scopine;498-45-3;6,7-Epoxytropine;(1R,2R,4S,5S,7s)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol;Z5LGM3Q28U;498-46-4;(1R,2R,4S,5S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol;rel-(1R,2R,4S,5S,7s)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol;Pseudoscopine;Scopanol;Scopin;7-Epoxytropine;UNII-Z5LGM3Q28U;SCHEMBL9889341;CHEMBL4303435;CHEMBL4303536;SCHEMBL18577687;DTXSID301151677;DTXSID801030466;HMS3656M14;HMS3884D08;HY-B0459;MFCD06658282;s2545;AKOS015919589;AKOS025400980;AC-3388;CCG-266261;S0912;SW219096-1;AB01566856_01;A871709;Q7434451;1.ALPHA.H,5.ALPHA.H-TROPAN-3.ALPHA.-OL, 6.BETA.,7.BETA.-EPOXY-;(1alpha,2beta,4beta,5alpha,7beta)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02.4]nonan-7-ol;(1.ALPHA.,2.BETA.,4.BETA.,5.ALPHA.,7.BETA.)-9-METHYL-3-OXA-9-AZATRICYCLO(3.3.1.02,4)NONAN-7-OL;3-Oxa-9-azatricyclo(3.3.1.0(2,4))nonan-7-ol, 9-methyl-, (1alpha,2beta,4beta,5alpha,7beta)-;3-Oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol, 9-methyl-, (1alpha,2beta,4beta,5alpha,7alpha)-

Suppliers and Price of Scopine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TCI Chemical
Scopine >98.0%(T)
200mg
$ 218.00

Chem-Impex
Scopine
25MG
$ 58.24

AvaChem
Scopine
5g
$ 850.00

AvaChem
Scopine
1g
$ 295.00

AvaChem
Scopine
100mg
$ 65.00

Arctom
rel-(1R,2R,4S,5S,7s)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol ≥98%
5mg
$ 8.00

Arctom
rel-(1R,2R,4S,5S,7s)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol ≥98%
50mg
$ 18.00

Arctom
rel-(1R,2R,4S,5S,7s)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol ≥98%
10mg
$ 11.00

Arctom
rel-(1R,2R,4S,5S,7s)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol ≥98%
250mg
$ 53.00

Arctom
Scopine ≥98%
20mg
$ 40.00

Total 137 raw suppliers

Chemical Property of Scopine Edit

Chemical Property:

Vapor Pressure:0.000427mmHg at 25°C
Melting Point:73.0 to 77.0 °C
Refractive Index:1.573
Boiling Point:281.3oC at 760 mmHg
PKA:14?+-.0.20(Predicted)
Flash Point:123.9oC
PSA：36.00000
Density:1.284 g/cm3
LogP:-0.47100
Storage Temp.:Inert atmosphere,Store in freezer, under -20°C
Solubility.:Dichloromethane; Methanol
XLogP3:-0.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:155.094628657
Heavy Atom Count:11
Complexity:179

Purity/Quality:

97% Min ^*data from raw suppliers

Scopine >98.0%(T) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C2CC(CC1C3C2O3)O
Isomeric SMILES:CN1[C@@H]2CC(C[C@H]1[C@H]3[C@@H]2O3)O
Uses Scopin is an Intermediate in the synthesis of Scopine Methobromide (Tiotropium EP Impurity G) (S199985), an impurity of Tiotropium (T444850), an muscarinic receptor antagonist and bronchodilator.

Technology Process of Scopine

There total 23 articles about Scopine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.3%