3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylpropylamine hydrochloride

Base Information

Chemical Name:3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylpropylamine hydrochloride
CAS No.:912275-39-9
Molecular Formula:C₁₈H₁₇F₆NO*ClH
Molecular Weight:413.79
Hs Code.:

Synonyms:3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylpropylamine hydrochloride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylpropylamine hydrochloride

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Technology Process of 3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylpropylamine hydrochloride

There total 1 articles about 3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylpropylamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 912275-37-7
tert-butyl [3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylpropyl]carbamate

: 912275-39-9
3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylpropylamine hydrochloride

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; dichloromethane; at 20 ℃; for 1h;

Reference yield: 94.0%

: 912275-39-9
3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylpropylamine hydrochloride

: 403-43-0
4-fluorobenzoyl chloride

: N-[3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylpropyl]-4-fluorobenzoic acid amide

Guidance literature:: With triethylamine; In dichloromethane; at 0 ℃; for 0.5h;

Reference yield: 93.0%

: 68947-43-3
1-methylpiperidine-4-carboxylic acid

: 912275-39-9
3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylpropylamine hydrochloride

: N-[3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylpropyl]-1-methylpiperidine-4-carboxamide

Guidance literature:: With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In dichloromethane; at 20 ℃; for 20h;