benzyloxycarbonylmethyl (2S,3R)-3-tertbutyloxy-2-(((9H-fluoren-9-ylmethoxy)carbonyl)amino)butanoate

Base Information

Chemical Name:benzyloxycarbonylmethyl (2S,3R)-3-tertbutyloxy-2-(((9H-fluoren-9-ylmethoxy)carbonyl)amino)butanoate
CAS No.:1419234-23-3
Molecular Formula:C₃₂H₃₅NO₇
Molecular Weight:545.632
Hs Code.:

Synonyms:benzyloxycarbonylmethyl (2S,3R)-3-tertbutyloxy-2-(((9H-fluoren-9-ylmethoxy)carbonyl)amino)butanoate

Suppliers and Price of benzyloxycarbonylmethyl (2S,3R)-3-tertbutyloxy-2-(((9H-fluoren-9-ylmethoxy)carbonyl)amino)butanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of benzyloxycarbonylmethyl (2S,3R)-3-tertbutyloxy-2-(((9H-fluoren-9-ylmethoxy)carbonyl)amino)butanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of benzyloxycarbonylmethyl (2S,3R)-3-tertbutyloxy-2-(((9H-fluoren-9-ylmethoxy)carbonyl)amino)butanoate

There total 1 articles about benzyloxycarbonylmethyl (2S,3R)-3-tertbutyloxy-2-(((9H-fluoren-9-ylmethoxy)carbonyl)amino)butanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 71989-35-0,138797-71-4
Fmoc-Thr(tBu)-OH

: 5437-45-6
Benzyl bromoacetate

: 1419234-23-3
benzyloxycarbonylmethyl (2S,3R)-3-tertbutyloxy-2-(((9H-fluoren-9-ylmethoxy)carbonyl)amino)butanoate

Guidance literature:: With tetra-(n-butyl)ammonium iodide; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 20 ℃;
DOI:10.1002/anie.201204538

Reference yield: 89.0%

: 29022-11-5
N-(fluoren-9-ylmethoxycarbonyl)glycine

: 35661-60-0
Fmoc-Leu-OH

: 35661-39-3,136132-75-7
N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine

: 1419234-23-3
benzyloxycarbonylmethyl (2S,3R)-3-tertbutyloxy-2-(((9H-fluoren-9-ylmethoxy)carbonyl)amino)butanoate

: 71989-31-6
Fmoc-Pro-OH

: 71989-18-9
Fmoc-Glu(OtBu)-OH

: 71989-38-3,118488-18-9,204384-67-8
Fmoc-Tyr(tBu)-OH

: 71989-35-0,138797-71-4
Fmoc-Thr(tBu)-OH

: 118584-90-0
N-α-Fmoc-N-ε-[5-(dimethylamino)naphthalene-1-sulfonyl]-L-lysine

: 1419234-26-6
C₅₄H₇₆N₁₀O₁₇S

Guidance literature:: N-(fluoren-9-ylmethoxycarbonyl)glycine; With 6-chloro-3-((dimethylamino)(dimethyliminio)methyl)-1H-benzo[d][1,2,3]triazol-3-ium-1-olatehexafluorophosphate(V); N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 1h;

With piperidine; In dichloromethane; at 20 ℃; for 0.0333333h;

Fmoc-Leu-OH; N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine; benzyloxycarbonylmethyl (2S,3R)-3-tertbutyloxy-2-(((9H-fluoren-9-ylmethoxy)carbonyl)amino)butanoate; Fmoc-Pro-OH; Fmoc-Glu(OtBu)-OH; Fmoc-Tyr(tBu)-OH; Fmoc-Thr(tBu)-OH; N-α-Fmoc-N-ε-[5-(dimethylamino)naphthalene-1-sulfonyl]-L-lysine; Further stages;
DOI:10.1002/anie.201204538

Reference yield: 87.0%

: 35661-60-0
Fmoc-Leu-OH

: 35661-39-3,136132-75-7
N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine

: 1419234-23-3
benzyloxycarbonylmethyl (2S,3R)-3-tertbutyloxy-2-(((9H-fluoren-9-ylmethoxy)carbonyl)amino)butanoate

: 71989-31-6
Fmoc-Pro-OH

: 71989-18-9
Fmoc-Glu(OtBu)-OH

: 71989-38-3,118488-18-9,204384-67-8
Fmoc-Tyr(tBu)-OH

: 71989-35-0,138797-71-4
Fmoc-Thr(tBu)-OH

: 1419234-21-1
C₃₄H₅₁N₇O₁₂

Guidance literature:: benzyloxycarbonylmethyl (2S,3R)-3-tertbutyloxy-2-(((9H-fluoren-9-ylmethoxy)carbonyl)amino)butanoate; With 6-chloro-3-((dimethylamino)(dimethyliminio)methyl)-1H-benzo[d][1,2,3]triazol-3-ium-1-olatehexafluorophosphate(V); N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 1h;

With piperidine; In dichloromethane; at 20 ℃; for 0.0333333h;

Fmoc-Leu-OH; N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine; Fmoc-Pro-OH; Fmoc-Glu(OtBu)-OH; Fmoc-Tyr(tBu)-OH; Fmoc-Thr(tBu)-OH; Further stages;
DOI:10.1002/anie.201204538