Trifluoro-methanesulfonic acid 3,3-dimethyl-2-oxo-4-triethylsilanyloxy-cyclohex-(Z)-ylidenemethyl ester

Base Information

• Chemical Name: Trifluoro-methanesulfonic acid 3,3-dimethyl-2-oxo-4-triethylsilanyloxy-cyclohex-(Z)-ylidenemethyl ester
• CAS No.: 131011-07-9
• Molecular Formula: C₁₆H₂₇F₃O₅SSi
• Molecular Weight: 416.534

Synonyms:Trifluoro-methanesulfonic acid 3,3-dimethyl-2-oxo-4-triethylsilanyloxy-cyclohex-(Z)-ylidenemethyl ester

Chemical Property of Trifluoro-methanesulfonic acid 3,3-dimethyl-2-oxo-4-triethylsilanyloxy-cyclohex-(Z)-ylidenemethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Trifluoro-methanesulfonic acid 3,3-dimethyl-2-oxo-4-triethylsilanyloxy-cyclohex-(Z)-ylidenemethyl ester

There total 5 articles about Trifluoro-methanesulfonic acid 3,3-dimethyl-2-oxo-4-triethylsilanyloxy-cyclohex-(Z)-ylidenemethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,2-dimethyl-1,3-cyclohexanedione (562-13-0) → Trifluoro-methanesulfonic acid 3,3-dimethyl-2-oxo-4-triethylsilanyloxy-cyclohex-(Z)-ylidenemethyl ester (131011-07-9)

Guidance literature:

Multi-step reaction with 4 steps

1: catechol borane, oxazaborolidine / toluene / -78 °C

2: imidazole / dimethylformamide / 23 °C

3: NaH, THF

4: 1.) NaH / 1.) THF, 23 deg C, 2.) -40 deg C

With tetrahydrofuran; 1H-imidazole; (S)-oxazaborolidine; sodium hydride; benzo[1,3,2]dioxaborole; In N,N-dimethyl-formamide; toluene;

DOI:10.1021/ja00180a064

Reference yield:

triethylsilyl chloride (994-30-9) → Trifluoro-methanesulfonic acid 3,3-dimethyl-2-oxo-4-triethylsilanyloxy-cyclohex-(Z)-ylidenemethyl ester (131011-07-9)

Guidance literature:

Multi-step reaction with 3 steps

1: imidazole / dimethylformamide / 23 °C

2: NaH, THF

3: 1.) NaH / 1.) THF, 23 deg C, 2.) -40 deg C

With tetrahydrofuran; 1H-imidazole; sodium hydride; In N,N-dimethyl-formamide;

DOI:10.1021/ja00180a064

Reference yield:

(S)-3-hydroxy-2,2-dimethylcyclohexanone (61447-86-7) → Trifluoro-methanesulfonic acid 3,3-dimethyl-2-oxo-4-triethylsilanyloxy-cyclohex-(Z)-ylidenemethyl ester (131011-07-9)

Guidance literature:

Multi-step reaction with 3 steps

1: imidazole / dimethylformamide / 23 °C

2: NaH, THF

3: 1.) NaH / 1.) THF, 23 deg C, 2.) -40 deg C

With tetrahydrofuran; 1H-imidazole; sodium hydride; In N,N-dimethyl-formamide;

DOI:10.1021/ja00180a064

upstream raw materials:

N,N-phenylbistrifluoromethane-sulfonimide

triethylsilyl chloride

2,2-dimethyl-1,3-cyclohexanedione

(S)-3-hydroxy-2,2-dimethylcyclohexanone

Downstream raw materials:

(1aR,4aS,7S,7aS)-7-[(R)-3-(tert-Butyl-diphenyl-silanyloxy)-1-methyl-propyl]-3-[3,3-dimethyl-2-oxo-4-triethylsilanyloxy-cyclohex-(E)-ylidenemethyl]-4a,7-dimethyl-1a,2,4a,5,6,7-hexahydro-1-oxa-cyclopropa[d]indene-4-carboxylic acid methyl ester

(1aR,4aS,7S,7aS)-7-[(R)-3-(tert-Butyl-diphenyl-silanyloxy)-1-methyl-propyl]-3-((1S,4S)-3,3-dimethyl-2-oxo-7-oxa-bicyclo[2.2.1]hept-1-ylmethyl)-4a,7-dimethyl-1a,2,4a,5,6,7-hexahydro-1-oxa-cyclopropa[d]indene-4-carboxylic acid methyl ester

(1S,7R,7aS)-7-Acetoxy-1-[(R)-3-(tert-butyl-diphenyl-silanyloxy)-1-methyl-propyl]-5-((1S,4S)-3,3-dimethyl-2-oxo-7-oxa-bicyclo[2.2.1]hept-1-ylmethyl)-1,7a-dimethyl-2,6,7,7a-tetrahydro-1H-indene-4-carboxylic acid methyl ester

C₄₄H₅₉ClO₇Si

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 131011-07-9 Trifluoro-methanesulfonic acid 3,3-dimethyl-2-oxo-4-triethylsilanyloxy-cyclohex-(Z)-ylidenemethyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send