2-Ethoxybenzaldehyde

Base Information

• Chemical Name: 2-Ethoxybenzaldehyde
• CAS No.: 613-69-4
• Molecular Formula: C9H10O2
• Molecular Weight: 150.177
• Hs Code.: 29122990
• European Community (EC) Number: 210-349-2
• NSC Number: 1783
• UNII: 7LT24CX9U3
• DSSTox Substance ID: DTXSID2060624
• Nikkaji Number: J99.993H
• Wikidata: Q72471279
• Mol file: 613-69-4.mol

Synonyms:2-ETHOXYBENZALDEHYDE;613-69-4;o-Ethoxybenzaldehyde;Benzaldehyde, 2-ethoxy-;Benzaldehyde, o-ethoxy-;2-Ethoxy benzaldehyde;Benzaldehyde, ethoxy-;2-ethoxy-benzaldehyde;7LT24CX9U3;NSC 1783;NSC-1783;EINECS 210-349-2;AI3-01358;ethoxy benzaldehyde;MFCD00003316;ortho-Ethoxybenzaldehyde;Ethoxybenzaldehyde, 2-;Salicylaldehyde Ethyl Ether;UNII-7LT24CX9U3;Integrase inhibitor, R2{2};SCHEMBL535646;2-Ethoxybenzaldehyde, >=97%;DTXSID2060624;BDBM93342;NSC1783;STK397319;AKOS000119720;CS-W018149;DS-3185;AM20050245;E0058;FT-0612205;EN300-16100;L10017;A833188;J-509285;Z53833343;F2190-0617

Chemical Property of 2-Ethoxybenzaldehyde

Chemical Property:

• Appearance/Colour: clear yellow to light brown liquid
• Vapor Pressure: 1.06E-08mmHg at 25°C
• Melting Point: 20-22oC
• Refractive Index: n20/D 1.543(lit.)
• Boiling Point: 247.9 °C at 760 mmHg
• Flash Point: 91.7 °C
• PSA: 26.30000
• Density: 1.06 g/cm³
• LogP: 1.89780
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Sensitive.: Air Sensitive
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 150.068079557
• Heavy Atom Count: 11
• Complexity: 123

Purity/Quality:

99.5% ^*data from raw suppliers

2-Ethoxybenzaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39-37/39-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCOC1=CC=CC=C1C=O
• Uses: 2-Ethoxybenzaldehyde was used to study the 1,3-dipolar cycloaddition reactions.

Technology Process of 2-Ethoxybenzaldehyde

There total 28 articles about 2-Ethoxybenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

2-ethoxybenzyl alcohol (71672-75-8) → 2-ethoxylbenzaldehyde (613-69-4)

Guidance literature:

With chromium(VI)-SiO₂; In diethyl ether; dichloromethane; at 20 ℃; for 24h;

DOI:10.1016/S0040-4039(01)00975-3

Reference yield: 88.0%

ethyl bromide (74-96-4) + salicylaldehyde (90-02-8) → 2-ethoxylbenzaldehyde (613-69-4)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 21h;

DOI:10.1039/b103181n

Reference yield: 87.0%

2-Ethoxybenzaldehyd-2,4-dinitrophenylhydrazon → 2-ethoxylbenzaldehyde (613-69-4)

Guidance literature:

With aluminum oxide; HMTAB; In toluene; for 0.5h; Heating;

DOI:10.1002/jccs.200700020

upstream raw materials:

diethyl sulfate

salicylaldehyde

ethyl iodide

2-ethoxyphenylmagnesium bromide

Downstream raw materials:

2-ethoxy cinnamic acid

3((E)-2-ethoxy-benzylidene)-dihydro-furan-2-one

1-(2-ethoxy-phenyl)-propan-1-ol

AM-879/41297482

Refernces

• 1、 Kim, Hun Young,Oh, Kyungsoo,Si, Tengda. "One-Pot Direct Oxidation of Primary Amines to Carboxylic Acids through Tandem ortho-Naphthoquinone-Catalyzed and TBHP-Promoted Oxidation Sequence". supporting information. p. 18150 - 18155. Retrieved 2021/12/09.
• 2、 -. "Method for synthesizing aromatic aldehyde through iron catalyzed oxidation allyl aromatic compound". Paragraph 0090-0092; 0150. . Retrieved 2019/06/27.