2(3H)-Furanone,3-(acetyloxy)dihydro-4,4-dimethyl-, (3R)-

Base Information

Chemical Name:2(3H)-Furanone,3-(acetyloxy)dihydro-4,4-dimethyl-, (3R)-
CAS No.:28227-36-3
Molecular Formula:C8H12 O4
Molecular Weight:172.181
Hs Code.:
Mol file:28227-36-3.mol

Synonyms:2(3H)-Furanone,3-(acetyloxy)dihydro-4,4-dimethyl-, (R)-; 2(3H)-Furanone,dihydro-3-hydroxy-4,4-dimethyl-, acetate, D-(-)- (8CI); (R)-(-)-Pantolactoneacetate; D-O-Acetylpantolactone; D-Pantolactone acetate

Suppliers and Price of 2(3H)-Furanone,3-(acetyloxy)dihydro-4,4-dimethyl-, (3R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2(3H)-Furanone,3-(acetyloxy)dihydro-4,4-dimethyl-, (3R)-

Chemical Property:

Boiling Point:263.9°Cat760mmHg
Flash Point:130.4°C
Density:1.14g/cm³

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2(3H)-Furanone,3-(acetyloxy)dihydro-4,4-dimethyl-, (3R)-

There total 5 articles about 2(3H)-Furanone,3-(acetyloxy)dihydro-4,4-dimethyl-, (3R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.94%

: 75-36-5
acetyl chloride

: 599-04-2
(R)-Pantolacton

: 28227-36-3
(R)-acetic acid 4,4-dimethyl-2-oxo-tetrahydrofuran-3-yl ester

Guidance literature:: With dmap; triethylamine; In dichloromethane; at 0 - 5 ℃;
DOI:10.1016/j.bmc.2019.115069

Reference yield:

: 108-24-7
acetic anhydride

: 599-04-2
(R)-Pantolacton

: 28227-36-3
(R)-acetic acid 4,4-dimethyl-2-oxo-tetrahydrofuran-3-yl ester

Guidance literature:: With pyridine;
DOI:10.1021/ja01864a037

Reference yield:

: 75-36-5
acetyl chloride

: 79-50-5
pantolactone

: 28227-36-3
(R)-acetic acid 4,4-dimethyl-2-oxo-tetrahydrofuran-3-yl ester

: 28387-34-0
(S)-2-acetoxy-3,3-dimethyl-γ-butyrolactone

Guidance literature:: acetyl chloride; pantolactone; With pyridine; at 20 ℃; for 19h;

With Bac_. stearothermophilus hydrolase; In phosphate buffer; at 37 ℃; for 3.56667h; pH=7.3; Title compound not separated from byproducts;
DOI:10.1016/S0957-4166(00)00465-1