Benzaldehyde 4-bromophenylhydrazone

Base Information

• Chemical Name: Benzaldehyde 4-bromophenylhydrazone
• CAS No.: 16917-43-4
• Molecular Formula: C13H11 Br N2
• Molecular Weight: 275.148
• Mol file: 16917-43-4.mol

Synonyms:Benzaldehyde 4-bromophenylhydrazone;BRN 0745200;Benzaldehyde, (p-bromophenyl)hydrazone;N-[(E)-benzylideneamino]-4-bromoaniline;16917-43-4;4-15-00-00283 (Beilstein Handbook Reference);SCHEMBL11426658;AKOS003238384;LS-24937

Chemical Property of Benzaldehyde 4-bromophenylhydrazone

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 371.5°Cat760mmHg
• Flash Point: 178.5°C
• PSA: 24.39000
• Density: 1.33g/cm³
• LogP: 3.96810
• XLogP3: 4.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 274.01056
• Heavy Atom Count: 16
• Complexity: 216

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C=NNC2=CC=C(C=C2)Br
• Isomeric SMILES: C1=CC=C(C=C1)/C=N/NC2=CC=C(C=C2)Br

Technology Process of Benzaldehyde 4-bromophenylhydrazone

There total 7 articles about Benzaldehyde 4-bromophenylhydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

4-bromophenylhydrazine hydrochloride (622-88-8,41931-18-4) + benzaldehyde (100-52-7) → benzaldehyde 4-bromophenylhydrazone (16917-43-4)

Guidance literature:

With sodium acetate; In ethanol; water; at 20 ℃;

DOI:10.1016/S0968-0896(02)00048-2

Reference yield:

tetrachloromethane (56-23-5) + bromine (7726-95-6) + benzaldehyde phenylhydrazone (588-64-7) → (4-bromophenyl)hydrazine (589-21-9) + benzaldehyde 4-bromophenylhydrazone (16917-43-4) + benzaldehyde-(2,4-dibromo-phenylhydrazone) (10477-86-8) + N-α-bromobenzylidene-N'-2,4-dibromophenylhydrazine (2516-46-3)

Guidance literature:

at -10 - -5 ℃;

Reference yield:

benzaldehyde (100-52-7) + (4-bromophenyl)hydrazine (589-21-9) → benzaldehyde 4-bromophenylhydrazone (16917-43-4)

Guidance literature:

With ethanol;

upstream raw materials:

benzaldehyde

(4-bromophenyl)hydrazine

benzaldehyde phenylhydrazone

tetrachloromethane

Downstream raw materials:

N-α-bromobenzylidene-N'-2,4-dibromophenylhydrazine

5-bromobenzopyrazole-3-carboxylic acid

1-(4-bromophenyl)-3,5-diphenyl-1H-1,2,4-triazole

[2-(4-bromo-phenyl)-5-phenyl-2H-[1,2,4]triazol-3-yl]-methanol

Refernces

• 1、 Bian, Xue-Wei,Zhang, Ling,Shoberu, Adedamola,Zou, Jian-Ping. "Mn(III)-mediated phosphinoylation of aldehyde hydrazones: Direct “one-pot” synthesis of α-iminophosphine oxides from aldehydes". supporting information. . Retrieved 2021/04/02.
• 2、 Janardhanan, Jith C.,James, Kiran,Puthuvakkal, Anisha,Bhaskaran, Rasmi P.,Suresh, Cherumuttathu H.,Praveen, Vakayil K.,Manoj, Narayanapillai,Babu, Beneesh P.. "Synthesis of hybrid polycycles containing fused hydroxy benzofuran and 1H-indazoles via a domino cyclization reaction". . p. 10166 - 10175. Retrieved 2019/07/03.