2,4-Dicyclohexylphenol

Base Information

• Chemical Name: 2,4-Dicyclohexylphenol
• CAS No.: 35406-29-2
• Molecular Formula: C18H26O
• Molecular Weight: 258.404
• DSSTox Substance ID: DTXSID6067917
• Nikkaji Number: J422.340C
• Wikidata: Q81994595
• Mol file: 35406-29-2.mol

Synonyms:2,4-Dicyclohexylphenol;Phenol, 2,4-dicyclohexyl-;35406-29-2;Oprea1_074266;SCHEMBL918287;DTXSID6067917

Chemical Property of 2,4-Dicyclohexylphenol

Chemical Property:

• Vapor Pressure: 1.78E-05mmHg at 25°C
• Boiling Point: 353.3°Cat760mmHg
• Flash Point: 166.2°C
• PSA: 20.23000
• Density: 1.032g/cm³
• LogP: 5.48760
• XLogP3: 6.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 258.198365449
• Heavy Atom Count: 19
• Complexity: 263

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCC(CC1)C2=CC(=C(C=C2)O)C3CCCCC3

Technology Process of 2,4-Dicyclohexylphenol

There total 7 articles about 2,4-Dicyclohexylphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

1-bromocyclohexane (108-85-0) + phenol (108-95-2,27073-41-2) → 2-cyclohexylphenol (119-42-6) + 2,6-dicyclohexylphenol (4821-19-6) + 2,4-dicyclohexylphenol (35406-29-2) + p-cyclohexylphenol (1131-60-8)

Guidance literature:

at 110 - 120 ℃; for 96h;

DOI:10.1080/00397919608003808

Reference yield:

cyclohexanol (108-93-0) + phenol (108-95-2,27073-41-2) → 2-cyclohexylphenol (119-42-6) + 2,6-dicyclohexylphenol (4821-19-6) + 2,4-dicyclohexylphenol (35406-29-2) + p-cyclohexylphenol (1131-60-8)

Guidance literature:

1-butyl-3-methylimidazolium heptachlorodiindate (III); at 120 ℃; for 4h; Product distribution / selectivity; In ionic liquid;

Reference yield:

cyclohexene (110-83-8) + phenol (108-95-2,27073-41-2) → cyclohexylphenyl ether (2206-38-4) + 2-cyclohexylphenol (119-42-6) + 2,6-dicyclohexylphenol (4821-19-6) + 2,4-dicyclohexylphenol (35406-29-2) + p-cyclohexylphenol (1131-60-8)

Guidance literature:

With glyceryl sulfate; at 80 ℃; for 2.5h; Product distribution; oth. temperature, oth. ratio of reactants, oth. time;

upstream raw materials:

cyclohexene

phenol

1-bromocyclohexane

cyclohexanol

Downstream raw materials:

2-cyclohexylphenol

Refernces

• 1、 Berkessel, Albrecht,Guenther, Thomas,Wang, Qifang,Neudoerfl, Joerg-M.. "Titanium salalen catalysts based on cis-1,2-diaminocyclohexane: Enantioselective epoxidation of terminal non-conjugated olefins with H 2O2". supporting information. p. 8467 - 8471. Retrieved 2013/09/02.
• 2、 -. "ALKYLATION OF HYDROXYARENES WITH OLEFINS, ALCOHOLS AND ETHERS IN IONIC LIQUIDS". Page/Page column 18-19. . Retrieved 2008/06/13.