2-Indolinethione, 1-methyl-

Base Information

• Chemical Name: 2-Indolinethione, 1-methyl-
• CAS No.: 13637-38-2
• Molecular Formula: C9H9 N S
• Molecular Weight: 163.243
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID80159767
• Nikkaji Number: J401.798F
• Wikidata: Q83028141
• Mol file: 13637-38-2.mol

Synonyms:13637-38-2;2-INDOLINETHIONE, 1-METHYL-;1-methyl-3H-indole-2-thione;1-Methyl-2-indolinethione;1-Methylindoline-2-thione;1-METHYL-1,3-DIHYDRO-INDOLE-2-THIONE;BRN 1526437;1,3-Dihydro-1-methyl-2H-indole-2-thione;1-methyl-2,3-dihydro-1H-indole-2-thione;2H-Indole-2-thione, 1,3-dihydro-1-methyl-;N-methyl thio-oxindole;SCHEMBL8999008;DTXSID80159767;AKOS006276816;LS-83482;CS-0300848;EN300-79104

Chemical Property of 2-Indolinethione, 1-methyl-

Chemical Property:

• Vapor Pressure: 0.0208mmHg at 25°C
• Boiling Point: 251.1°Cat760mmHg
• Flash Point: 105.7°C
• PSA: 35.33000
• Density: 1.23g/cm³
• LogP: 2.07130
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 163.04557046
• Heavy Atom Count: 11
• Complexity: 178

Purity/Quality:

99% ^*data from raw suppliers

1,3-dihydro-1-methyl-2H-Indole-2-thione 97.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN1C(=S)CC2=CC=CC=C21

Technology Process of 2-Indolinethione, 1-methyl-

There total 11 articles about 2-Indolinethione, 1-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

N-methyl-2-indolinone (61-70-1) → 1-methyl-2-indolinethione (13637-38-2)

Guidance literature:

With tetraphosphorus decasulfide; sodium hydrogencarbonate; In tetrahydrofuran; at 20 ℃; for 4h;

DOI:10.1021/jo0479866

Reference yield: 75.0%

N-Ethynylthio-N-methylbenzenamine (104501-70-4) → 1-methyl-2-indolinethione (13637-38-2)

Guidance literature:

In benzene; for 1.5h; Heating;

DOI:10.1055/s-1985-31400

Reference yield:

N-methyl-2-indolinone (61-70-1) + P2 S5 + sodium carbonate (497-19-8) → 1-methyl-2-indolinethione (13637-38-2)

Guidance literature:

In tetrahydrofuran;

upstream raw materials:

N-methyl-2-indolinone

N-Ethynylthio-N-methylbenzenamine

1-methyl-1H-indole-2-thiol

1-methyl-1H-indole-2,3-dione

Downstream raw materials:

N-phenyl (1-methyl-2-thioxo-3-indolinyl)carboxamide

3-(4'-carbomethoxybenzoyl)-1-methyl-2-indolinethione

1-methylindole

3-ethyl-1-methyl-1H-indole