3,5-DIMETHYLTHIOANISOLE

Base Information

• Chemical Name: 3,5-DIMETHYLTHIOANISOLE
• CAS No.: 66794-11-4
• Molecular Formula: C₉H₁₂S
• Molecular Weight: 152.26
• Mol file: 66794-11-4.mol

Synonyms:(3,5-dimethylphenyl)(methyl)sulfane

Chemical Property of 3,5-DIMETHYLTHIOANISOLE

Chemical Property:

• Boiling Point: 120 °C(Press: 15 Torr)
• Density: 0.99±0.1 g/cm3(Predicted)

Purity/Quality:

99% ^*data from raw suppliers

3,5-Dimethylthioanisole ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,5-DIMETHYLTHIOANISOLE

There total 4 articles about 3,5-DIMETHYLTHIOANISOLE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

3,5-Dimethylthiophenol (38360-81-5) + methyl iodide (74-88-4) → (3,5-dimethylphenyl)(methyl)sulfane (66794-11-4)

Guidance literature:

With potassium carbonate; tetrabutylammomium bromide; In dimethyl sulfoxide; at 20 ℃; for 16h;

Reference yield: 81.0%

3,5-dimethylphenyl iodide (22445-41-6) + dimethyl sulfoxide (67-68-5,8070-53-9) → (3,5-dimethylphenyl)(methyl)sulfane (66794-11-4)

Guidance literature:

With zinc(II) fluoride; copper(I) bromide; at 150 ℃; for 36h; Sealed tube; Under air;

DOI:10.1039/c1cc10795j

Reference yield: 71.0%

5-bromo-1,3-xylene (556-96-7) + dimethyl sulfoxide (67-68-5,8070-53-9) → (3,5-dimethylphenyl)(methyl)sulfane (66794-11-4)

Guidance literature:

With copper(l) iodide; zinc(II) fluoride; at 150 ℃; for 36h; Sealed tube; Under air;

DOI:10.1039/c1cc10795j

upstream raw materials:

3,5-Dimethylthiophenol

dimethyl sulfate

methyl iodide

5-bromo-1,3-xylene

Downstream raw materials:

N-phenyl-S-(3,5-dimethylphenyl)-S-methylsulfoximine

S-(3,5-methyl)phenyl-S-methylsulfoximine

1,1-bis(2,6-dimethyl-4-(methylthio)phenyl)silacyclobutane

4-bromo-3,5-dimethylthioanisole

Refernces

• 1、 Luo, Fang,Pan, Changduo,Li, Liping,Chen, Fan,Cheng, Jiang. "Copper-mediated methylthiolation of aryl halides with DMSO". scheme or table. p. 5304 - 5306. Retrieved 2011/06/21.