(2R)-2-amino-6-hydroxyhexanoic acid

Base Information

Chemical Name:(2R)-2-amino-6-hydroxyhexanoic acid
CAS No.:16509-61-8
Molecular Formula:C₆H₁₃NO₃
Molecular Weight:147.174
Hs Code.:
UNII:FTB8ZT2FBB
Nikkaji Number:J58.432K
Mol file:16509-61-8.mol

Synonyms:(2R)-2-amino-6-hydroxyhexanoic acid;6-HYDROXY-D-NORLEUCINE;16509-61-8;d-6-hydroxynorleucine;FTB8ZT2FBB;D-Norleucine, 6-hydroxy-;Norleucine, 6-hydroxy-, D-;SCHEMBL2684333;AKOS037653284;DB02233;GS-8024;PD060100;NS00068818;EN300-298772

Suppliers and Price of (2R)-2-amino-6-hydroxyhexanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
D-6-HYDROXYNORLEUCINE 95.00%
5MG
$ 595.00

American Custom Chemicals Corporation
D-6-HYDROXYNORLEUCINE 95.00%
1MG
$ 542.85

Total 5 raw suppliers

Chemical Property of (2R)-2-amino-6-hydroxyhexanoic acid

Chemical Property:

XLogP3:-2.8
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:147.08954328
Heavy Atom Count:10
Complexity:105

Purity/Quality:

99% ^*data from raw suppliers

D-6-HYDROXYNORLEUCINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C(CCO)CC(C(=O)O)N
Isomeric SMILES:C(CCO)C[C@H](C(=O)O)N

Technology Process of (2R)-2-amino-6-hydroxyhexanoic acid

There total 9 articles about (2R)-2-amino-6-hydroxyhexanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 5462-80-6
rac-6-hydroxynorleucine

: 305-77-1,5462-80-6,6033-32-5,16509-61-8
L-ε-hydroxynorleucine

Guidance literature:: DOI:10.1021/jo00326a061

Reference yield: 75.0%

: 161562-28-3
2-((R)-2-Oxo-oxepan-3-yl)-isoindole-1,3-dione

: 16509-61-8
(R)-2-amino-6-hydroxy-hexanoic acid

Guidance literature:: With sulfuric acid; for 6h; Heating;
DOI:10.1016/0040-4039(94)02278-J

Reference yield:

: 28957-33-7
(R)-3-amino-azepan-2-one

: 16509-61-8
(R)-2-amino-6-hydroxy-hexanoic acid

Guidance literature:: Multi-step reaction with 5 steps

1: dioxane

2: DMF

3: 96 percent / N₂O₃ / acetic acid / 1 h / 15 °C

4: 55 percent / 1,2-dimethoxy-ethane / 1 h / Heating

5: 75 percent / 15percent H₂SO₄ / 6 h / Heating

With dinitrogen trioxide; sulfuric acid; N,N-dimethyl-formamide; In 1,4-dioxane; 1,2-dimethoxyethane; acetic acid;
DOI:10.1016/0040-4039(94)02278-J