2-[1-(trimethylsiloxy)-3-phenyl-(E)-2-propenyl]cyclohexanone

Base Information

• Chemical Name: 2-[1-(trimethylsiloxy)-3-phenyl-(E)-2-propenyl]cyclohexanone
• CAS No.: 84896-21-9
• Molecular Formula: C₁₈H₂₆O₂Si
• Molecular Weight: 302.489
• Mol file: 84896-21-9.mol

Synonyms:2-[1-(trimethylsiloxy)-3-phenyl-(E)-2-propenyl]cyclohexanone

Chemical Property of 2-[1-(trimethylsiloxy)-3-phenyl-(E)-2-propenyl]cyclohexanone

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 2-[1-(trimethylsiloxy)-3-phenyl-(E)-2-propenyl]cyclohexanone

There total 5 articles about 2-[1-(trimethylsiloxy)-3-phenyl-(E)-2-propenyl]cyclohexanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

1-(Trimethylsilyloxy)cyclohexene (6651-36-1) + 3-phenyl-propenal (104-55-2) → 2-[1-(trimethylsiloxy)-3-phenyl-(E)-2-propenyl]cyclohexanone (84896-21-9)

Guidance literature:

With samarium diiodide bis(tetrahydrofuran); In dichloromethane; for 6.5h; Ambient temperature;

DOI:10.1016/S0040-4020(98)00791-1

Reference yield: 51.0%

(E)-3-phenylpropenal (14371-10-9) + 1-(Trimethylsilyloxy)cyclohexene (6651-36-1) → 2-[1-(trimethylsiloxy)-3-phenyl-(E)-2-propenyl]cyclohexanone (84896-21-9)

Guidance literature:

tetrabutyl ammonium fluoride; In tetrahydrofuran; at -78 ℃; for 4h;

DOI:10.1021/jo00155a003

Reference yield: 33.0%

(E)-3-phenylpropenal (14371-10-9) + chloro-trimethyl-silane (75-77-4) + cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) → (E)-2-(1-hydroxy-3-phenylallyl)cyclohexanone (130751-64-3) + 2-[1-(trimethylsiloxy)-3-phenyl-(E)-2-propenyl]cyclohexanone (84896-21-9)

Guidance literature:

chloro-trimethyl-silane; cyclohexanone; With triethylamine; ytterbium(III) triflate; In dichloromethane; at 20 ℃;

(E)-3-phenylpropenal; In dichloromethane; at 20 ℃; for 48h;

DOI:10.1071/CH04006

upstream raw materials:

(E)-3-phenylpropenal

1-(Trimethylsilyloxy)cyclohexene

3-phenyl-propenal

chloro-trimethyl-silane