(2,2-Difluoroethyl)-N-phenylamine

Base Information

Chemical Name:(2,2-Difluoroethyl)-N-phenylamine
CAS No.:405-17-4
Molecular Formula:C₈H₉F₂N
Molecular Weight:157.163
Hs Code.:
European Community (EC) Number:876-192-2

Synonyms:N-(2,2-difluoroethyl)aniline;(2,2-Difluoroethyl)-N-phenylamine;405-17-4;difluorophenyl-ethylamine;SCHEMBL632545;MLBYYTORZPAXDZ-UHFFFAOYSA-N;MFCD12807383;CS-0234866;EN300-148672

Suppliers and Price of (2,2-Difluoroethyl)-N-phenylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of (2,2-Difluoroethyl)-N-phenylamine

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:157.07030562
Heavy Atom Count:11
Complexity:100

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)NCC(F)F

Technology Process of (2,2-Difluoroethyl)-N-phenylamine

There total 7 articles about (2,2-Difluoroethyl)-N-phenylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 430-67-1
2,2-difluorethylamine

: 98-80-6
phenylboronic acid

: 405-17-4
N-(2,2-difluoroethyl)aniline

Guidance literature:: With copper diacetate; triethylamine; In acetonitrile; at 80 ℃; Molecular sieve;
DOI:10.1039/C8OB01581C

Reference yield: 59.0%

: 381-73-7
Difluoroacetic acid

: 62-53-3
aniline

: 405-17-4
N-(2,2-difluoroethyl)aniline

Guidance literature:: With potassium phosphate; 18-crown-6 ether; phenylsilane; In tetrahydrofuran; at 80 ℃; for 12h; Glovebox; Molecular sieve; Schlenk technique;
DOI:10.1002/adsc.202000679

Reference yield: 19.0%

: 67-56-1
methanol

: 399-01-9
N-(2,2-Difluoroethyl)-N-methylaniline

: 405-17-4
N-(2,2-difluoroethyl)aniline

: N-(2,2-Difluoro-1-methoxyethyl)-N-methylaniline

Guidance literature:: With potassium hydroxide; Ambient temperature; electrolysis: carbon anode and Pt cathode; constant current 13.9 mA/cm²; charge passed: 3.3 F/mol;
DOI:10.1021/jo00082a018