2-(5-tert-butyl-4-chloro-2-methyl-2H-pyrazol-3-yl)-6-(2-chloro-phenyl)-4-methoxy-3H-imidazo[4,5-c]pyridine

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Chemical Name:2-(5-tert-butyl-4-chloro-2-methyl-2H-pyrazol-3-yl)-6-(2-chloro-phenyl)-4-methoxy-3H-imidazo[4,5-c]pyridine
CAS No.:1332876-25-1
Molecular Formula:C₂₁H₂₁Cl₂N₅O
Molecular Weight:430.337
Hs Code.:

Synonyms:2-(5-tert-butyl-4-chloro-2-methyl-2H-pyrazol-3-yl)-6-(2-chloro-phenyl)-4-methoxy-3H-imidazo[4,5-c]pyridine

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Chemical Property of 2-(5-tert-butyl-4-chloro-2-methyl-2H-pyrazol-3-yl)-6-(2-chloro-phenyl)-4-methoxy-3H-imidazo[4,5-c]pyridine

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Technology Process of 2-(5-tert-butyl-4-chloro-2-methyl-2H-pyrazol-3-yl)-6-(2-chloro-phenyl)-4-methoxy-3H-imidazo[4,5-c]pyridine

There total 8 articles about 2-(5-tert-butyl-4-chloro-2-methyl-2H-pyrazol-3-yl)-6-(2-chloro-phenyl)-4-methoxy-3H-imidazo[4,5-c]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1332877-05-0
N-(3-amino-6-(2-chlorophenyl)-2-methoxypyridin-4-yl)-3-tert-butyl-4-chloro-1-methyl-1H-pyrazole-5-carboxamide

: 1332876-25-1
2-(5-tert-butyl-4-chloro-2-methyl-2H-pyrazol-3-yl)-6-(2-chloro-phenyl)-4-methoxy-3H-imidazo[4,5-c]pyridine

Guidance literature:: N-(3-amino-6-(2-chlorophenyl)-2-methoxypyridin-4-yl)-3-tert-butyl-4-chloro-1-methyl-1H-pyrazole-5-carboxamide; acetic acid; at 90 ℃; for 2h;

With sodium hydrogencarbonate; In water; ethyl acetate;

Reference yield:

: 1332876-27-3
5-tert-butyl-4-chloro-2-methyl-2H-pyrazole-3-carboxylic acid [6-(2-chloro-phenyl)-2-methoxy-3-nitro-pyridin-4-yl]-amide

: 1332876-25-1
2-(5-tert-butyl-4-chloro-2-methyl-2H-pyrazol-3-yl)-6-(2-chloro-phenyl)-4-methoxy-3H-imidazo[4,5-c]pyridine

Guidance literature:: With iron; acetic acid; at 100 ℃; for 3h;

Reference yield:

: 2897-43-0
2,6-dichloro-3-nitropyridin-4-amine

: 1332876-25-1
2-(5-tert-butyl-4-chloro-2-methyl-2H-pyrazol-3-yl)-6-(2-chloro-phenyl)-4-methoxy-3H-imidazo[4,5-c]pyridine

Guidance literature:: Multi-step reaction with 5 steps

1.1: methanol / 2 h / 100 °C / Sealed tube

2.1: caesium carbonate / 1,4-dioxane; water / 15 h / 90 °C / Inert atmosphere

3.1: sodium hydride / tetrahydrofuran / 3 - 7 °C

3.2: 1 h / 1 - 10 °C

4.1: hydrogen / Pt(sulfided)/C / ethyl acetate / 3 h / 1810.07 - 2068.65 Torr

5.1: acetic acid / 2 h / 90 °C

With hydrogen; sodium hydride; caesium carbonate; acetic acid; In tetrahydrofuran; 1,4-dioxane; methanol; water; ethyl acetate; 2.1: Suzuki Coupling;