4-(1-[4-(pyridin-2-ylmethoxy)phenyl]cyclobutyl)phenyl trifluoromethanesulfonate

Base Information

• Chemical Name: 4-(1-[4-(pyridin-2-ylmethoxy)phenyl]cyclobutyl)phenyl trifluoromethanesulfonate
• CAS No.: 1141359-79-6
• Molecular Formula: C₂₃H₂₀F₃NO₄S
• Molecular Weight: 463.477
• Mol file: 1141359-79-6.mol

Synonyms:4-(1-[4-(pyridin-2-ylmethoxy)phenyl]cyclobutyl)phenyl trifluoromethanesulfonate

Chemical Property of 4-(1-[4-(pyridin-2-ylmethoxy)phenyl]cyclobutyl)phenyl trifluoromethanesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of 4-(1-[4-(pyridin-2-ylmethoxy)phenyl]cyclobutyl)phenyl trifluoromethanesulfonate

There total 1 articles about 4-(1-[4-(pyridin-2-ylmethoxy)phenyl]cyclobutyl)phenyl trifluoromethanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-{1-[4-(pyridin-2-ylmethoxy)phenyl]cyclobutyl}phenol (1141359-77-4) + Phenyl triflate (17763-67-6) → 4-(1-[4-(pyridin-2-ylmethoxy)phenyl]cyclobutyl)phenyl trifluoromethanesulfonate (1141359-79-6)

Guidance literature:

4-{1-[4-(pyridin-2-ylmethoxy)phenyl]cyclobutyl}phenol; With lithium hexamethyldisilazane; In tetrahydrofuran; for 0.0833333h;

Phenyl triflate; In tetrahydrofuran; at 0 ℃; for 1.5h;

Reference yield:

methanol (67-56-1) + carbon monoxide (201230-82-2) + 4-(1-[4-(pyridin-2-ylmethoxy)phenyl]cyclobutyl)phenyl trifluoromethanesulfonate (1141359-79-6) → methyl 4-{1-[4-(pyridin-2-ylmethoxy)phenyl]cyclobutyl}benzoate (1141359-80-9)

Guidance literature:

With triethylamine; 1,1'-bis-(diphenylphosphino)ferrocene; palladium diacetate; In N,N-dimethyl-formamide; at 80 ℃; for 16h; under 760.051 Torr;

upstream raw materials:

4-{1-[4-(pyridin-2-ylmethoxy)phenyl]cyclobutyl}phenol

Phenyl triflate

Downstream raw materials:

methyl 4-{1-[4-(pyridin-2-ylmethoxy)phenyl]cyclobutyl}benzoate