7-Methoxy-1-phenyl-3,4-dihydroisoquinoline

Base Information

Chemical Name:7-Methoxy-1-phenyl-3,4-dihydroisoquinoline
CAS No.:104576-31-0
Molecular Formula:C₁₆H₁₅NO
Molecular Weight:237.301
Hs Code.:
DSSTox Substance ID:DTXSID601267231
Nikkaji Number:J875.274E

Synonyms:7-methoxy-1-phenyl-3,4-dihydroisoquinoline;SCHEMBL2340188;XRJNMEBBXFLFBW-UHFFFAOYSA-N;DTXSID601267231;1-Phenyl-7-methoxy-3,4-dihydroisoquinoline;3,4-Dihydro-7-methoxy-1-phenylisoquinoline;104576-31-0

Suppliers and Price of 7-Methoxy-1-phenyl-3,4-dihydroisoquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 7-Methoxy-1-phenyl-3,4-dihydroisoquinoline

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:237.115364102
Heavy Atom Count:18
Complexity:306

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC2=C(CCN=C2C3=CC=CC=C3)C=C1

Technology Process of 7-Methoxy-1-phenyl-3,4-dihydroisoquinoline

There total 14 articles about 7-Methoxy-1-phenyl-3,4-dihydroisoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 1262842-01-2
C₂₃H₂₃NO₃S

: 104576-31-0
1-phenyl-7-methoxy-3,4-dihydro-isoquinoline

Guidance literature:: With sodium hydroxide; In water; dimethyl sulfoxide; at 70 ℃; for 1.5h; regiospecific reaction;
DOI:10.1080/00397911.2011.568659

Reference yield: 87.0%

: 702-23-8
2-(4-Methoxyphenyl)ethanol

: 100-47-0
benzonitrile

: 104576-31-0
1-phenyl-7-methoxy-3,4-dihydro-isoquinoline

Guidance literature:: With 2-fluoropyridine; trifluoromethylsulfonic anhydride; In 1,2-dichloro-ethane; at 0 - 80 ℃; for 12.5h; Reagent/catalyst; Temperature;
DOI:10.1021/acs.orglett.9b00534

Reference yield: 80.0%

: 3278-19-1
N-[2-(4-methoxyphenyl)ethyl]benzamide

: 104576-31-0
1-phenyl-7-methoxy-3,4-dihydro-isoquinoline

Guidance literature:: With 3-butyl-1-methyl-1H-imidazol-3-ium hexafluorophosphate; trichlorophosphate; at 95 - 100 ℃; for 183h; Inert atmosphere;
DOI:10.1016/j.mencom.2012.09.014