2-formyl[5-(phenylacetyl)-4,5,6,7-tetrahydrothieno][3,2-c]pyridine

Base Information

• Chemical Name: 2-formyl[5-(phenylacetyl)-4,5,6,7-tetrahydrothieno][3,2-c]pyridine
• CAS No.: 623565-04-8
• Molecular Formula: C₁₆H₁₅NO₂S
• Molecular Weight: 285.367
• Mol file: 623565-04-8.mol

Synonyms:2-formyl[5-(phenylacetyl)-4,5,6,7-tetrahydrothieno][3,2-c]pyridine

Chemical Property of 2-formyl[5-(phenylacetyl)-4,5,6,7-tetrahydrothieno][3,2-c]pyridine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-formyl[5-(phenylacetyl)-4,5,6,7-tetrahydrothieno][3,2-c]pyridine

There total 3 articles about 2-formyl[5-(phenylacetyl)-4,5,6,7-tetrahydrothieno][3,2-c]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

2-formyl-6,7-dihydro-4H-thieno[3,2-c]pyridine-5-carboxylic acid ethyl ester (623564-88-5) + phenylacetyl chloride (103-80-0) → 2-formyl[5-(phenylacetyl)-4,5,6,7-tetrahydrothieno][3,2-c]pyridine (623565-04-8)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 24h;

Reference yield: 89.0%

2-(formyl)-6,7-dihydrothieno[3,2-c]-5(4H)-pyridine (197237-97-1) + phenylacetyl chloride (103-80-0) → 2-formyl[5-(phenylacetyl)-4,5,6,7-tetrahydrothieno][3,2-c]pyridine (623565-04-8)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 24h;

Reference yield: 89.0%

2-(formyl)-6,7-dihydrothieno[3,2-c]-5(4H)-pyridine hydrochloride salt + phenylacetyl chloride (103-80-0) → 2-formyl[5-(phenylacetyl)-4,5,6,7-tetrahydrothieno][3,2-c]pyridine (623565-04-8)

Guidance literature:

2-(formyl)-6,7-dihydrothieno[3,2-c]-5(4H)-pyridine hydrochloride salt; phenylacetyl chloride; With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 24h;

With water; In N,N-dimethyl-formamide;

upstream raw materials:

2-formyl-6,7-dihydro-4H-thieno[3,2-c]pyridine-5-carboxylic acid ethyl ester

phenylacetyl chloride

2-(formyl)-6,7-dihydrothieno[3,2-c]-5(4H)-pyridine

Downstream raw materials:

4-nitrobenzy-6-[(acetyloxy)[5-(phenylacetyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl]methyl]-6-bromo-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate

4-nitrobenzyl-6-[(acetyloxy)[5(phenylacetyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl]methyl]-6-bromo-7-oxo-4-thia-1-azabicyclo[3,2,0]hept-2-ene-2-carboxylate