2-amino-5-chlorobenzophenone methylimine

Base Information

• Chemical Name: 2-amino-5-chlorobenzophenone methylimine
• CAS No.: 344246-75-9
• Molecular Formula: C₁₄H₁₃ClN₂
• Molecular Weight: 244.724
• Mol file: 344246-75-9.mol

Synonyms:2-amino-5-chlorobenzophenone methylimine

Chemical Property of 2-amino-5-chlorobenzophenone methylimine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-amino-5-chlorobenzophenone methylimine

There total 2 articles about 2-amino-5-chlorobenzophenone methylimine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-chloro-2-trichloroacetylaminobenzophenone (26381-66-8) → 2-amino-5-chlorobenzophenone methylimine (344246-75-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 16 percent / ethanol / 3 h / 60 °C

2: TiCl₄ / benzene

With titanium tetrachloride; In ethanol; benzene;

DOI:10.1248/cpb.29.2135

Reference yield:

5-chloro-2-aminobenzophenone (719-59-5) + methylamine (74-89-5) → 2-amino-5-chlorobenzophenone methylimine (344246-75-9)

Guidance literature:

With titanium tetrachloride; In benzene;

DOI:10.1248/cpb.29.2135

Reference yield: 89.0%

2-amino-5-chlorobenzophenone methylimine (344246-75-9) → 2-amino-5-chloro-N-methylbenzhydrylamine (80170-90-7)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 2h; Ambient temperature;

DOI:10.1248/cpb.29.2135

upstream raw materials:

5-chloro-2-aminobenzophenone

methylamine

5-chloro-2-trichloroacetylaminobenzophenone

Downstream raw materials:

2-amino-5-chloro-N-methylbenzhydrylamine

syn-5-chloro-2-trifluoroacetamidobenzophenone methylimine

syn-5-chloro-2-trichloroacetamidobenzophenone methylimine

6-chloro-3,4-dihydro-3-methyl-4-phenyl-4-trichloromethyl-2(1H)-quinazolinone

Refernces