o-carbomethoxybenzoic acid anilide

Base Information

• Chemical Name: o-carbomethoxybenzoic acid anilide
• CAS No.: 53241-98-8
• Molecular Formula: C₁₅H₁₃NO₃
• Molecular Weight: 255.273
• Mol file: 53241-98-8.mol

Synonyms:o-carbomethoxybenzoic acid anilide

Chemical Property of o-carbomethoxybenzoic acid anilide

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of o-carbomethoxybenzoic acid anilide

There total 16 articles about o-carbomethoxybenzoic acid anilide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

phthalic acid dimethyl ester (131-11-3,64441-70-9) + aniline (62-53-3) → o-carbomethoxybenzoic acid anilide (53241-98-8)

Guidance literature:

In tetrahydrofuran; for 2h; Heating;

DOI:10.1021/jf050746m

Reference yield: 41.0%

methyl 2-cyanobenzoate (6587-24-2) + 1-acetyl-2-phenylhydrazine (114-83-0) → N'-acetyl-N'-phenylacetohydrazide (38604-74-9) + o-carbomethoxybenzoic acid anilide (53241-98-8)

Guidance literature:

With bis-[(trifluoroacetoxy)iodo]benzene; In neat (no solvent); at 40 ℃; for 2h; Sealed tube;

DOI:10.1021/acs.joc.7b01215

Reference yield:

phthalanilic acid (4727-29-1) + dimethyl sulfate (77-78-1) → o-carbomethoxybenzoic acid anilide (53241-98-8)

Guidance literature:

With potassium carbonate; In neat (no solvent, solid phase); Milling; Green chemistry;

upstream raw materials:

N-phenylphthalimide

methanol

phthalic monoacid monomethyl ester chloride

aniline

Downstream raw materials:

N-phenylphthalimide

phthalanilic acid