Lauramine oxide

Base Information

• Chemical Name: Lauramine oxide
• CAS No.: 1643-20-5
• Deprecated CAS: 135526-66-8,160714-02-3,163221-07-6,177162-47-9,73502-08-6,209122-49-6,311814-25-2,244235-92-5,607690-42-6,1616935-99-9,1447712-24-4,2306325-97-1,934560-91-5,160714-02-3,163221-07-6,177162-47-9,209122-49-6,244235-92-5,311814-25-2,607690-42-6,73502-08-6
• Molecular Formula: C14H31NO
• Molecular Weight: 229.406
• Hs Code.: 29299090
• European Community (EC) Number: 216-700-6
• UN Number: 3249
• UNII: 4F6FC4MI8W
• DSSTox Substance ID: DTXSID1020514
• Nikkaji Number: J53.935J
• Wikipedia: Lauryldimethylamine_oxide
• Wikidata: Q6501952
• RXCUI: 1364388
• Metabolomics Workbench ID: 122975
• ChEMBL ID: CHEMBL1233973
• Mol file: 1643-20-5.mol

Synonyms:Ammonyx LO;DDAO;dodecyldimethylamine N-oxide;dodecyldimethylamine oxide;hexyldimethylamine oxide;lauryldimethylamine oxide;LDAO;N,N-dimethyldodecyclamine N-oxide;N,N-dimethyldodecylamine-N-oxide;N-dodecyl-N,N-dimethylamine N-oxide

Chemical Property of Lauramine oxide

Chemical Property:

• Appearance/Colour: Clear yellow lquid
• Vapor Pressure: 6.88E-05mmHg at 25°C
• Melting Point: 132-133 °C(lit.)
• Refractive Index: n20/D 1.378
• Boiling Point: 100oC
• PKA: 4.79±0.40(Predicted)
• Flash Point: 94oC
• PSA: 29.43000
• Density: 0.996 g/mL at 20oC
• LogP: 4.50240
• Storage Temp.: 2-8°C
• Sensitive.: Hygroscopic
• Water Solubility.: Insoluble in water.
• XLogP3: 5.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 11
• Exact Mass: 229.240564612
• Heavy Atom Count: 16
• Complexity: 146
• Transport DOT Label: Poison

Purity/Quality:

30%min ^*data from raw suppliers

N,N-Dimethyldodecylamine N-oxide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Statements: 34-52/53
• Safety Statements: 26-36/37/39-45-27

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Other Uses -> Emulsifiers/Surfactants
• Canonical SMILES: CCCCCCCCCCCC[N+](C)(C)[O-]
• Uses: Barlox(R) 1260 is a concentrated cocoamine oxide surfactant. Barlox(R) 1260 can be used in a broad number of industriual cleaning applications where coupling, high foaming, detergency and compatibility are important. Product Data Sheet LDAO is suitable to use in crystallization of membrane proteins. It is also suitable to enhance the detection of high molecular weight proteins.

Technology Process of Lauramine oxide

There total 3 articles about Lauramine oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.4%

N,N-dimethylaminododecane (112-18-5,83855-86-1) → dodecyl-N,N-dimethylamine N-oxide (1643-20-5)

Guidance literature:

With dihydrogen peroxide; In water; at 100 ℃; for 6h;

Reference yield:

N,N-dimethylaminododecane (112-18-5,83855-86-1) → lauric acid (143-07-7) + formic acid (64-18-6) + dodecyl-N,N-dimethylamine N-oxide (1643-20-5)

Guidance literature:

With oxygen; ruthenium trichloride; In water; acetone; at 100 ℃; for 16h;

DOI:10.1039/c39830001530

Reference yield:

→ dodecyl-N,N-dimethylamine N-oxide (1643-20-5)

Guidance literature:

DOI:10.1021/bi00714a005 DOI:10.1007/BF02667031 DOI:10.1139/v65-423 DOI:10.1021/jo01266a026

upstream raw materials:

N,N-dimethylaminododecane

Downstream raw materials:

1-dodecene

N,N-dimethylaminododecane

Refernces

• 1、 Brycki, Bogumil,Szafran, Miroslaw. "Effect of pH on Carbon-13 NMR Spectra of N-Dodecyl-N,N-dimethylamine Oxide Solution". . p. 535 - 543. Retrieved 1992.
• 2、 Sheng,Zajacek. "". . p. 588. Retrieved 1968.
• 3、 Germani, Raimondo,Orlandini, Matteo,Tiecco, Matteo,Del Giacco, Tiziana. "Novel low viscous, green and amphiphilic N-oxides/phenylacetic acid based Deep Eutectic Solvents". . p. 233 - 239. Retrieved 2017.
• 4、 Applebury et al.. "". . p. 3448,3449. Retrieved 1974.
• 5、 Chen, Qing-Yun,Dai, Longhao,Guo, Yong,Huang, Meiwei,Shen, Qing,Su, Qin,Su, Zhaoben,Wu, Chengying,Zhao, Zhi-Gang. "The surface properties of amine oxides with a fluoroether chain". . . Retrieved 2021/06/12.
• 6、 Rauchdi, Mariem,Ait Ali, Mustapha,Roucoux, Alain,Denicourt-Nowicki, Audrey. "Novel access to verbenone via ruthenium nanoparticles-catalyzed oxidation of Α-pinene in neat water". . p. 266 - 273. Retrieved 2017/12/06.