(2R,5R)-5-cyclohexyl-2-<(1R,2S)-1-benzyl-2-hydroxy-2phenylethyl>-1,3-dioxolan-4-one

Base Information

Chemical Name:(2R,5R)-5-cyclohexyl-2-<(1R,2S)-1-benzyl-2-hydroxy-2phenylethyl>-1,3-dioxolan-4-one
CAS No.:121097-26-5
Molecular Formula:C₂₄H₂₈O₄
Molecular Weight:380.484
Hs Code.:

Synonyms:(2R,5R)-5-cyclohexyl-2-<(1R,2S)-1-benzyl-2-hydroxy-2phenylethyl>-1,3-dioxolan-4-one

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Chemical Property of (2R,5R)-5-cyclohexyl-2-<(1R,2S)-1-benzyl-2-hydroxy-2phenylethyl>-1,3-dioxolan-4-one

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Technology Process of (2R,5R)-5-cyclohexyl-2-<(1R,2S)-1-benzyl-2-hydroxy-2phenylethyl>-1,3-dioxolan-4-one

There total 2 articles about (2R,5R)-5-cyclohexyl-2-<(1R,2S)-1-benzyl-2-hydroxy-2phenylethyl>-1,3-dioxolan-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 133797-18-9
C₂₀H₃₀O₃Si

: 100-52-7
benzaldehyde

: 121097-26-5
(2R,5R)-5-cyclohexyl-2-<(1R,2S)-1-benzyl-2-hydroxy-2phenylethyl>-1,3-dioxolan-4-one

Guidance literature:: With trimethylsilyl trifluoromethanesulfonate; In dichloromethane; at -78 ℃; for 3h;
DOI:10.1021/ja00009a029

Reference yield:

: 100-52-7
benzaldehyde

: 116279-22-2
(C₆H₁₁)CHOCO₂Si(CH₃)3C₃H₄(C₆H₅)

: 133868-42-5
(2R,5R)-2-((1R,2R)-1-Benzyl-2-hydroxy-2-phenyl-ethyl)-5-cyclohexyl-[1,3]dioxolan-4-one

: 121097-26-5,133868-42-5
(2R,5R)-2-((1S,2S)-1-Benzyl-2-hydroxy-2-phenyl-ethyl)-5-cyclohexyl-[1,3]dioxolan-4-one

Guidance literature:: With trimethylsilyl trifluoromethanesulfonate; In dichloromethane; at -78 ℃; for 6h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
DOI:10.1021/ja00194a061