Technology Process of (1R,2R)-(4-fluorophenyl)-2,3-glycidol
There total 4 articles about (1R,2R)-(4-fluorophenyl)-2,3-glycidol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
styrene monooxygenase;
In
aq. phosphate buffer;
at 30 ℃;
for 15h;
pH=7;
enantioselective reaction;
DOI:10.1039/c4ob02186j
- Guidance literature:
-
With
Escherichia coli BL21 harboring the plasmid pET28a(+) encoding the styAB gene from Pseudomonas sp. LQ26;
for 16h;
pH=6.5;
optical yield given as %ee;
enantioselective reaction;
aq. phosphate buffer;
Enzymatic reaction;
DOI:10.1039/c0cc04360e
- Guidance literature:
-
Multi-step reaction with 2 steps
1: tetrahydrofuran / Cooling
2: Escherichia coli BL21 harboring the plasmid pET28a(+) encoding the styAB gene from Pseudomonas sp. LQ26 / 16 h / pH 6.5 / aq. phosphate buffer; Enzymatic reaction
With
Escherichia coli BL21 harboring the plasmid pET28a(+) encoding the styAB gene from Pseudomonas sp. LQ26;
In
tetrahydrofuran;
DOI:10.1039/c0cc04360e
