Benzyldiphenylphosphine oxide

Base Information

• Chemical Name: Benzyldiphenylphosphine oxide
• CAS No.: 2959-74-2
• Molecular Formula: C19H17 O P
• Molecular Weight: 292.317
• NSC Number: 132554,130070
• DSSTox Substance ID: DTXSID10183772
• Nikkaji Number: J108.207H
• Wikidata: Q63398190
• ChEMBL ID: CHEMBL1730140
• Mol file: 2959-74-2.mol

Synonyms:Benzyldiphenylphosphine oxide;2959-74-2;Diphenylbenzylphosphine oxide;diphenylphosphorylmethylbenzene;Phosphine oxide, diphenyl(phenylmethyl)-;Phosphine oxide, benzyldiphenyl-;Diphenyl(phenylmethyl)phosphine oxide;BRN 2809334;benzyl(diphenyl)phosphine oxide;Phosphine oxide, benzyldiphenyl- (6CI,7CI,8CI);[BENZYL(PHENYL)PHOSPHOROSO]BENZENE;Benzyldiphenylphosphineoxide;MLS000595032;SCHEMBL518265;C19H17OP;CHEMBL1730140;DTXSID10183772;HMS2527F16;C19-H17-O-P;CAA95974;MFCD00015817;NSC130070;NSC132554;AKOS002364398;NSC 130070;NSC 132554;NSC-130070;NSC-132554;NCGC00245549-01;AS-64375;SMR000184418;[(DIPHENYLPHOSPHOROSO)METHYL]BENZENE;LS-106020;CS-0038626;W13583;Q63398190

Chemical Property of Benzyldiphenylphosphine oxide

Chemical Property:

• Vapor Pressure: 5.67E-07mmHg at 25°C
• Boiling Point: 423°Cat760mmHg
• Flash Point: 209.6°C
• Density: 1.15g/cm³
• XLogP3: 4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 292.101702159
• Heavy Atom Count: 21
• Complexity: 325

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)CP(=O)(C2=CC=CC=C2)C3=CC=CC=C3

Technology Process of Benzyldiphenylphosphine oxide

There total 100 articles about Benzyldiphenylphosphine oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

chloro-diphenylphosphine (1079-66-9,74391-44-9) + benzyl alcohol (100-51-6,185532-71-2) → benzyldiphenylphosphine oxide (2959-74-2)

Guidance literature:

chloro-diphenylphosphine; benzyl alcohol; With sodium iodide; In acetonitrile; at 20 - 80 ℃; for 12h; Inert atmosphere;

With dihydrogen peroxide; In water; acetonitrile; Temperature;

DOI:10.1016/j.tetlet.2016.04.035

Reference yield: 98.0%

benzyldiphenylphosphane (7650-91-1) → benzyldiphenylphosphine oxide (2959-74-2)

Guidance literature:

With water; Selectfluor; In acetonitrile; at 20 ℃; for 0.166667h;

DOI:10.1016/j.tetlet.2016.06.078

Reference yield: 98.0%

phenylacetonitrile (140-29-4) + Diphenylphosphine oxide (4559-70-0) → benzyldiphenylphosphine oxide (2959-74-2)

Guidance literature:

With tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; potassium tert-butylate; 2'-(di-tert-butylphosphanyl)-N,N-dimethyl-[1,1'-biphenyl]-2-amine; In 1,4-dioxane; at 120 ℃; for 16h; Reagent/catalyst; Inert atmosphere; Glovebox;

upstream raw materials:

ethanol

benzyl-dichloro-diphenyl-phosphorane

diphenyl-phosphinic acid

4-pyrone

Downstream raw materials:

diphenyl-phosphinic acid

diphenylphosphinoyl-phenyl-acetic acid

di(m-nitrophenyl)-p-nitrobenzylphosphine oxide

(2-methyl-1-butenyl)-benzene