methyl 2-(((tert-butoxycarbonyl)oxy)(4-methoxyphenyl)methyl)acrylate

Base Information

• Chemical Name: methyl 2-(((tert-butoxycarbonyl)oxy)(4-methoxyphenyl)methyl)acrylate
• CAS No.: 1132641-34-9
• Molecular Formula: C₁₇H₂₂O₆
• Molecular Weight: 322.358
• Mol file: 1132641-34-9.mol

Synonyms:methyl 2-(((tert-butoxycarbonyl)oxy)(4-methoxyphenyl)methyl)acrylate

Chemical Property of methyl 2-(((tert-butoxycarbonyl)oxy)(4-methoxyphenyl)methyl)acrylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 2-(((tert-butoxycarbonyl)oxy)(4-methoxyphenyl)methyl)acrylate

There total 2 articles about methyl 2-(((tert-butoxycarbonyl)oxy)(4-methoxyphenyl)methyl)acrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

di-tert-butyl dicarbonate (24424-99-5) + methyl 2-[hydroxy(4-methoxyphenyl)methyl]prop-2-enoate (115240-92-1) → methyl 2-(((tert-butoxycarbonyl)oxy)(4-methoxyphenyl)methyl)acrylate (1132641-34-9)

Guidance literature:

With dmap; In dichloromethane;

DOI:10.1016/j.tet.2013.11.028

Reference yield:

4-methoxy-benzaldehyde (123-11-5) → methyl 2-(((tert-butoxycarbonyl)oxy)(4-methoxyphenyl)methyl)acrylate (1132641-34-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 1,4-diaza-bicyclo[2.2.2]octane / methanol

2: dmap / dichloromethane

With 1,4-diaza-bicyclo[2.2.2]octane; dmap; In methanol; dichloromethane;

DOI:10.1016/j.tet.2013.11.028

Reference yield: 99.0%

methyl 2-(((tert-butoxycarbonyl)oxy)(4-methoxyphenyl)methyl)acrylate (1132641-34-9) + 4-methyl-N-(3-phenylprop-2-yn-1-yl)benzenesulfonamide (305837-95-0) → C28H27NO5S

Guidance literature:

With hydroquinidine (anthraquinone-1,4-diyl) diether; In para-xylene; at 50 ℃; for 96h; Reagent/catalyst; Solvent; Time; enantioselective reaction;

DOI:10.1055/s-0034-1379072

upstream raw materials:

di-tert-butyl dicarbonate

methyl 2-[hydroxy(4-methoxyphenyl)methyl]prop-2-enoate

4-methoxy-benzaldehyde

Downstream raw materials:

C₂₄H₂₀N₂O₃S

C₂₄H₂₀N₂O₃S

C₂₀H₁₉NO₃

C₃₄H₂₉NO₅