115240-92-1

Basic information

• Product Name: Benzenepropanoic acid, β-hydroxy-4-methoxy-α-methylene-, methyl ester
• Synonyms: Benzenepropanoic acid, β-hydroxy-4-methoxy-α-methylene-, methyl ester;Methyl2-[hydroxyl(4-methoxyphenyl)methyl]prop-2-enoat
• CAS NO: 115240-92-1
• Molecular Formula: C₁₂H₁₄O₄
• Molecular Weight: 222.24
• Mol File: 115240-92-1.mol
• Article Data: 90

Chemical Properties

• Melting Point: 62-63 °C
• Boiling Point: 361.3±42.0 °C(Predicted)
• Appearance: /
• Density: 1.155±0.06 g/cm3(Predicted)
• PKA: 12.92±0.20(Predicted)
• CAS DataBase Reference: Benzenepropanoic acid, β-hydroxy-4-methoxy-α-methylene-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanoic acid, β-hydroxy-4-methoxy-α-methylene-, methyl ester(115240-92-1)
• EPA Substance Registry System: Benzenepropanoic acid, β-hydroxy-4-methoxy-α-methylene-, methyl ester(115240-92-1)

Safety Data

• Hazardous Substances Data: 115240-92-1(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 123-11-5 4-methoxy-benzaldehyde 
• 140-88-5 ethyl acrylate 
• 1132641-34-9 methyl 2-(((tert-butoxycarbonyl)oxy)(4-methoxyphenyl)methyl)acrylate 
• 5445-17-0 Methyl 2-bromopropionate 
• 292638-85-8 acrylic acid methyl ester 

Downstream Products

• 124957-41-1 methyl 2-[acetoxy(4-methoxyphenyl)methyl]acrylate 
• 671778-72-6 methyl (2Z)-3-(4'-methoxyphenyl)-2-chloromethylpropenoate 
• 13048-81-2 (E)-3-(4-methoxyphenyl)-2-methylacrylic acid 
• 1114965-88-6 C₁₄H₁₈O₄ 
• 1033505-41-7 C₁₄H₁₈O₄ 
• 1114965-90-0 C₁₅H₂₀O₄ 
• 1033505-43-9 C₁₅H₂₀O₄ 
• 1114965-91-1 C₁₉H₂₀O₄ 
• 1033505-45-1 C₁₉H₂₀O₄ 
• 1126630-73-6 C₁₉H₂₀O₅S 
• 1197422-63-1 methyl 2-[(4-hydroxyphenyl)methyl]-3-(4-methoxyphenyl)-3-oxopropanoate 
• 1379512-43-2 (Z)-methyl 2-((diethoxyphosphoryl)methyl)-3-(4-methoxyphenyl)acrylate 
• 1009376-01-5 (E)-methyl 2-(aminomethyl)-3-(4-methoxyphenyl)acrylate 
• 1132641-34-9 methyl 2-(((tert-butoxycarbonyl)oxy)(4-methoxyphenyl)methyl)acrylate 

Relevant articles and documents

Unexpected side reactions of imidazolium-based ionic liquids in the base-catalysed Baylis-Hillman reaction

Low yields are obtained when the Baylis-Hillman reaction is conducted in the presence of an imidazolium-based ionic liquid due to direct addition of the deprotonated imidazolium salt to the aldehyde. Ionic liquids are evidently not inert.

Piperonal as electrophile in the Baylis-Hillman reaction. A synthesis of hydroxy-β-piperonyl-γ-butyrolactone derivative

Aromatic aldehydes are reluctant to serve as substrates for the Baylis- Hillman reaction at all under the relatively mild conditions. In our research, we have achieved that piperonal could be an useful substrate in this reaction, employing ultrasound tech

Microwave-Assisted 1,3-Dioxa-[3,3]-Sigmatropic Rearrangement of Substituted Allylic Carbamates: Application to the Synthesis of Novel 1,3-Oxazine-2,4-dione Derivatives

In a first instance, the effect of the microwave irradiation on the 1,3-Dioxa-[3,3]-sigmatropic rearrangement of aryl allylic carbamates was investigated. Under these new conditions, the reaction acceleration was clearly highlighted compared to convention

Ligand-Dependent Regiodivergent Enantioselective Allylic Alkylations of α-Trifluoromethylated Ketones

The asymmetric introduction of the CF3 unit is a powerful tool for modifying pharmacokinetic properties and slowing metabolic degradation in medicinal chemistry. A catalytic and enantioselective addition of α-CF3 enolates allows for expeditious access to