tert-butyl 4-tert-butylphenyl ether

Base Information

• Chemical Name: tert-butyl 4-tert-butylphenyl ether
• CAS No.: 31603-95-9
• Molecular Formula: C₁₄H₂₂O
• Molecular Weight: 206.328
• Mol file: 31603-95-9.mol

Synonyms:1-(tert-butoxy)-4-(tert-butyl)benzene

Chemical Property of tert-butyl 4-tert-butylphenyl ether

Chemical Property:

• Vapor Pressure: 0.0137mmHg at 25°C

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl 4-tert-butylphenyl ether

There total 14 articles about tert-butyl 4-tert-butylphenyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

tert-Butyl 2,2,2-trichloroacetimidate (98946-18-0) + para-tert-butylphenol (98-54-4) → 1-(tert-butoxy)-4-(tert-butyl)benzene (31603-95-9)

Guidance literature:

With HNC₅H₂(C(CH₃)3)2CH₃⁽¹⁺⁾*N(SO₂CF₃)2^(1-)=(HNC₅H₂(C(CH₃)3)2CH₃)N(SO₂CF₃)2; In fluorobenzene; at 20 ℃; for 0.75h; Reagent/catalyst; Solvent; Catalytic behavior;

DOI:10.1021/acs.joc.1c00193

Reference yield: 89.0%

1-bromo-4-tert-butylbenzene (3972-65-4) + sodium t-butanolate (865-48-5) → 1-(tert-butoxy)-4-(tert-butyl)benzene (31603-95-9)

Guidance literature:

With di-tert-butyl (2'-methyl-[1,1'-biphenyl]-2-yl)phosphine; palladium diacetate; In toluene; at 100 ℃;

DOI:10.1021/jo001426z

Reference yield: 53.0%

1-bromo-4-tert-butylbenzene (3972-65-4) + sodium t-butanolate (865-48-5) → tert-butylbenzene (253185-03-4,253185-04-5) + 4,4'-di-tert-butylbiphenyl (1625-91-8) + 1-(tert-butoxy)-4-(tert-butyl)benzene (31603-95-9)

Guidance literature:

palladium diacetate; 1,1′-binaphthalene-2,2′-diylbis[bis(4-methylphenyl)phosphine]; In toluene; at 100 ℃;

DOI:10.1021/ja9640152

upstream raw materials:

tertiary butyl chloride

para-tert-butylphenol

isobutene

tert-butyl alcohol

Downstream raw materials:

3,5-dinitro-benzoic acid-(4-tert-butyl-phenyl ester)

4-tert-butyl-2-bromo-1-tert-butyloxy-benzene

para-tert-butylphenol

4-tert-butyl-4-fluorocyclohexa-2,5-dien-1-one