(6-BROMO-1,3-BENZODIOXOL-5-YL)METHANOL

Base Information

• Chemical Name: (6-BROMO-1,3-BENZODIOXOL-5-YL)METHANOL
• CAS No.: 6642-34-8
• Molecular Formula: C8H7 Br O3
• Molecular Weight: 231.046
• Hs Code.: 2932999099
• Mol file: 6642-34-8.mol

Synonyms:Piperonylalcohol, 6-bromo- (6CI,8CI); (6-Bromo-1,3-benzodioxol-5-yl)methanol;6-Bromopiperonyl alcohol; NSC 15641

Chemical Property of (6-BROMO-1,3-BENZODIOXOL-5-YL)METHANOL

Chemical Property:

• Vapor Pressure: 4.5E-05mmHg at 25°C
• Melting Point: 90-92°C
• Boiling Point: 336.1°C at 760 mmHg
• PKA: 13.82±0.10(Predicted)
• Flash Point: 157.1°C
• PSA: 38.69000
• Density: 1.768g/cm³
• LogP: 1.67010
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

(6-Bromo-1,3-benzodioxol-5-yl)methanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (6-BROMO-1,3-BENZODIOXOL-5-YL)METHANOL

There total 5 articles about (6-BROMO-1,3-BENZODIOXOL-5-YL)METHANOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.1%

6-bromo-3,4-methylenedioxybenzaldehyde (15930-53-7) + thiophenol (108-98-5) → 6-bromopiperonyl alcohol (6642-34-8) + 6-(phenylthio)benzo[1,3]dioxole-5-carbaldehyde (158719-70-1) + 2-bromo-4-hydroxy-5-phenylthiomethoxybenzaldehyde + 4-hydroxy-2-phenylthio-5-phenylthiomethoxybenzaldehyde

Guidance literature:

With sodium methylate; In dimethyl sulfoxide; at 130 ℃; for 0.05h;

DOI:10.1248/cpb.42.500

Reference yield: 30.9%

6-bromo-3,4-methylenedioxybenzaldehyde (15930-53-7) → 6-bromopiperonyl alcohol (6642-34-8) + 6-bromopiperonylic acid (60546-62-5) + 2-bromoisovanillin (2973-59-3) + 6-bromo-3-hydroxy-4-(6'-bromo-3',4'-methylenedioxybenzyloxy)benzaldehyde (75437-93-3)

Guidance literature:

With sodium methylate; In dimethyl sulfoxide; at 150 ℃; for 0.0194444h;

Reference yield: 30.9%

sodium methylate (124-41-4) + 6-bromo-3,4-methylenedioxybenzaldehyde (15930-53-7) → 6-bromopiperonyl alcohol (6642-34-8) + 6-bromopiperonylic acid (60546-62-5) + 2-bromoisovanillin (2973-59-3) + 6-bromo-3-hydroxy-4-(6'-bromo-3',4'-methylenedioxybenzyloxy)benzaldehyde (75437-93-3)

Guidance literature:

In dimethyl sulfoxide; at 150 ℃; for 0.0194444h;

upstream raw materials:

d⁽⁴⁾-methanol

sodium methylate

6-bromo-3,4-methylenedioxybenzaldehyde

thiophenol

Downstream raw materials:

6-bromo-3,4-methylenedioxybenzaldehyde

C₂₆H₂₁BrNO₂P

C₂₉H₃₉NO₄Si

[(1S,2S,4R,5S)-4-Benzyloxy-5-(tert-butyl-dimethyl-silanyloxy)-2-vinyl-cyclohexyl]-(6-bromo-benzo[1,3]dioxol-5-ylmethyl)-amine