4-(t-butyl)cyclohexylcarbonyl fluoride

Base Information

• Chemical Name: 4-(t-butyl)cyclohexylcarbonyl fluoride
• CAS No.: 1258145-52-6
• Molecular Formula: C₁₁H₁₉FO
• Molecular Weight: 186.27
• Mol file: 1258145-52-6.mol

Synonyms:4-(t-butyl)cyclohexylcarbonyl fluoride

Chemical Property of 4-(t-butyl)cyclohexylcarbonyl fluoride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(t-butyl)cyclohexylcarbonyl fluoride

There total 2 articles about 4-(t-butyl)cyclohexylcarbonyl fluoride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

2,3,4,5,6-pentafluorobenzophenone (1536-23-8) + C18H23NO2 (1336931-29-3) → 4-(t-butyl)cyclohexylcarbonyl fluoride (1258145-52-6) + 1-benzoyl-4-(4-cyanophenoxy)-2,3,5,6-tetrafluorobenzene (1336943-54-4)

Guidance literature:

With hydridotetakis(triphenylphosphine)rhodium(I); cis-1,2-bis-(diphenylphosphino)ethene; In chlorobenzene; for 3h; Inert atmosphere; Reflux;

DOI:10.1016/j.tet.2011.07.031

Reference yield: 80.0%

Hexafluorobenzene (392-56-3) + C18H26O2S (1258145-49-1) → 1,4-bis(4-methoxyphenylthio)-2,3,5,6-tetrafluorobenzene (1173915-06-4) + 4-(t-butyl)cyclohexylcarbonyl fluoride (1258145-52-6)

Guidance literature:

With hydridotetakis(triphenylphosphine)rhodium(I); 1,2-bis-(diphenylphosphino)ethane; In chlorobenzene; for 3h; Reflux; Inert atmosphere;

DOI:10.1016/j.tetlet.2010.09.009

upstream raw materials:

Hexafluorobenzene

C₁₈H₂₆O₂S

2,3,4,5,6-pentafluorobenzophenone

C₁₈H₂₃NO₂

Refernces

• 1、 Arisawa, Mieko,Yamada, Toru,Yamaguchi, Masahiko. "Rhodium-catalyzed interconversion between acid fluorides and thioesters controlled using heteroatom acceptors". supporting information; experimental part. p. 6090 - 6092. Retrieved 2011/01/04.