Repromicin

Base Information

Chemical Name:Repromicin
CAS No.:56689-42-0
Molecular Formula:C31H51 N O8
Molecular Weight:565.748
Hs Code.:
UNII:G5WU4SAO6B
DSSTox Substance ID:DTXSID501024032
Wikidata:Q27278808
NCI Thesaurus Code:C152193
ChEMBL ID:CHEMBL3138624
Mol file:56689-42-0.mol

Synonyms:antibiotic M-4365 G2;de-epoxy rosamicin;de-epoxy rosamicin phosphate;de-epoxy rosamicin sulfate;de-epoxy rosamicin tartrate, (R-(R*,R*))-isomer;de-epoxy rosamicin, (12Z)-isomer;de-epoxy rosamicin, dodecysulfate-(12E)-isomer;de-epoxy rosamicin, octadecanoate-(12E)-isomer;de-epoxy rosamicin, potassium dihydrogen phosphate;M-4365G2

Suppliers and Price of Repromicin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
REPROMICIN 95.00%
5MG
$ 498.04

Total 4 raw suppliers

Chemical Property of Repromicin

Chemical Property:

Vapor Pressure:2.44E-24mmHg at 25°C
Boiling Point:726°C at 760 mmHg
Flash Point:392.9°C
PSA：122.60000
Density:1.13g/cm³
LogP:3.45920
XLogP3:3.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:6
Exact Mass:565.36146759
Heavy Atom Count:40
Complexity:902

Purity/Quality:

99% ^*data from raw suppliers

REPROMICIN 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1C(C=C(C=CC(=O)C(CC(C(C(C(CC(=O)O1)O)C)OC2C(C(CC(O2)C)N(C)C)O)CC=O)C)C)C
Isomeric SMILES:CC[C@@H]1[C@H](/C=C(/C=C/C(=O)[C@@H](C[C@@H]([C@@H]([C@H]([C@@H](CC(=O)O1)O)C)O[C@H]2[C@@H]([C@H](C[C@H](O2)C)N(C)C)O)CC=O)C)\C)C
Uses Antibacterial.

Technology Process of Repromicin

There total 32 articles about Repromicin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 35834-26-5
rosaramicin

: 56689-42-0
12,13-de-epoxy-12,13-didehydrorosaramicin

Guidance literature:: With hydrogenchloride; titanium(III) chloride; In methanol; water; at 0 ℃; for 3h; pH 1.3;
DOI:10.1039/P19890000787

Reference yield: 57.1%

: 58947-83-4
12,13-de-epoxy-12,13-dehydro-20-dihydrorosaramicin

: 56689-42-0
12,13-de-epoxy-12,13-didehydrorosaramicin

Guidance literature:: With 1-methyl-1H-imidazole; [2,2]bipyridinyl; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; copper(I) triflate; In acetonitrile; at 20 ℃; for 1.5h;
DOI:10.1021/jacs.7b02875

Reference yield:

: 35834-26-5
rosaramicin

: 61486-91-7
12,13-de-epoxy-12,13-didehydrorosamicin 20-dimethyl acetal

: 56689-42-0
12,13-de-epoxy-12,13-didehydrorosaramicin

Guidance literature:: With hydrogenchloride; titanium(III) chloride; In methanol; water; at 0 ℃; for 3h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; pH 1.0;
DOI:10.1039/P19890000787