4-(Hydroxy-phenyl-methyl)-imidazole-1-sulfonic acid dimethylamide

Base Information

• Chemical Name: 4-(Hydroxy-phenyl-methyl)-imidazole-1-sulfonic acid dimethylamide
• CAS No.: 135799-03-0
• Molecular Formula: C₁₂H₁₅N₃O₃S
• Molecular Weight: 281.335
• Mol file: 135799-03-0.mol

Synonyms:4-(Hydroxy-phenyl-methyl)-imidazole-1-sulfonic acid dimethylamide

Chemical Property of 4-(Hydroxy-phenyl-methyl)-imidazole-1-sulfonic acid dimethylamide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 4-(Hydroxy-phenyl-methyl)-imidazole-1-sulfonic acid dimethylamide

There total 1 articles about 4-(Hydroxy-phenyl-methyl)-imidazole-1-sulfonic acid dimethylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzaldehyde (100-52-7) + 4-iodo-N,N-dimethyl-1H-imidazole-1-sulfonamide (135773-25-0) → 4-(Hydroxy-phenyl-methyl)-imidazole-1-sulfonic acid dimethylamide (135799-03-0)

Guidance literature:

With ethylmagnesium bromide; Yield given. Multistep reaction; 1) Et₂O, CH₂Cl₂, 30 min, r.t. 2) 16 h;

DOI:10.1021/jo00020a002

Reference yield: 98.0%

4-(Hydroxy-phenyl-methyl)-imidazole-1-sulfonic acid dimethylamide (135799-03-0) → 1-(1H-imidazol-4-yl)phenylmethanol (78892-29-2)

Guidance literature:

With sulfuric acid; for 16h; Heating;

DOI:10.1021/jo00020a002

upstream raw materials:

benzaldehyde

4-iodo-N,N-dimethyl-1H-imidazole-1-sulfonamide

Downstream raw materials:

1-(1H-imidazol-4-yl)phenylmethanol