135773-25-0Relevant articles and documents
Characterization of the binding site of the histamine H3 receptor. 1. Various approaches to the synthesis of 2-(1H-imidazol-4-yl)cyclopropylamine and histaminergic activity of (1R,2R)- and (1S,2S)-2-(1H-imidazol-4-yl)- cyclopropylamine
De Esch, Iwan J. P.,Vollinga, Roeland C.,Goubitz, Kees,Schenk, Henk,Appelberg, Ulf,Hacksell, Uli,Lemstra, Sylvia,Zuiderveld, Obbe P.,Hoffmann, Marcel,Leurs, Rob,Menge, Wiro M. P. B.,Timmerman, Henk
, p. 1115 - 1122 (1999)
Various approaches to the synthesis of all four stereoisomers of 2-(1H- imidazol-4-yl)cyclopropylamine (cyclopropylhistamine) are described. The rapid and convenient synthesis and resolution of trans-cyclopropylhistamine is reported. The absolute configur
Total synthesis of the putative structure of nagelamide D
Bhandari, Manojkumar R.,Sivappa, Rasapalli,Lovely, Carl J.
, p. 1535 - 1538 (2009)
A total synthesis of the putative structure of nagelamide D from imidazole is described. A Stille cross-coupling is used to construct the bis imidazole skeleton, and the pyrrolecarboxamides are introduced via a double Mitsunobu reaction using a pyrrolehyd
Certain Nitrogen Containing Bicyclic Chemical Entities for Treating Viral Infections
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Page/Page column 92; 93, (2010/08/18)
Provided are certain chemical entities, pharmaceutical compositions, and methods of treatment of a member of the flaviviradae family of viruses such as hepacivirus (Hepatitis C or HCV).