(2R,2′R)-2,2′-((2-iodo-1,3-phenylene)bis(oxy))dipropanoic acid

Base Information

• Chemical Name: (2R,2′R)-2,2′-((2-iodo-1,3-phenylene)bis(oxy))dipropanoic acid
• CAS No.: 1226896-33-8
• Molecular Formula: C₁₂H₁₃IO₆
• Molecular Weight: 380.136
• Mol file: 1226896-33-8.mol

Synonyms:(2R,2′R)-2,2′-((2-iodo-1,3-phenylene)bis(oxy))dipropanoic acid

Chemical Property of (2R,2′R)-2,2′-((2-iodo-1,3-phenylene)bis(oxy))dipropanoic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2R,2′R)-2,2′-((2-iodo-1,3-phenylene)bis(oxy))dipropanoic acid

There total 5 articles about (2R,2′R)-2,2′-((2-iodo-1,3-phenylene)bis(oxy))dipropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(2R,2'R)-dimethyl 2,2'-((2-iodo-1,3-phenylene)bis(oxy))dipropanoate (1255651-99-0) → (2R,2′R)-2,2′-((2-iodo-1,3-phenylene)bis(oxy))dipropanoic acid (1226896-33-8)

Guidance literature:

With sodium hydroxide; In tetrahydrofuran; methanol; at 20 ℃; for 5h;

DOI:10.1002/anie.202005181

Reference yield: 99.0%

(2R,2'R)-diethyl 2,2'-(2-iodo-1,3-phenylene)bis(oxy)dipropanoate (1226896-32-7) → (2R,2′R)-2,2′-((2-iodo-1,3-phenylene)bis(oxy))dipropanoic acid (1226896-33-8)

Guidance literature:

(2R,2'R)-diethyl 2,2'-(2-iodo-1,3-phenylene)bis(oxy)dipropanoate; With water; sodium hydroxide; In tetrahydrofuran; methanol; at 20 ℃; for 12h;

With hydrogenchloride; In tetrahydrofuran; methanol; water; at 0 ℃;

DOI:10.1002/anie.200907352

Reference yield: 99.0%

dimethyl-2,2'-((2-(diacetoxy-λ3-iodanyl)-1,3-phenylene)bis(oxy))(2R,2'R)-dipropionate (1255651-84-3) → (2R,2′R)-2,2′-((2-iodo-1,3-phenylene)bis(oxy))dipropanoic acid (1226896-33-8)

Guidance literature:

With sodium hydroxide; In tetrahydrofuran; methanol; at 0 - 20 ℃;

DOI:10.1002/chem.201603022

upstream raw materials:

(2R,2'R)-diethyl 2,2'-(2-iodo-1,3-phenylene)bis(oxy)dipropanoate

recorcinol

2-iodoresorcinol

(2R,2'R)-dimethyl 2,2'-((2-iodo-1,3-phenylene)bis(oxy))dipropanoate

Downstream raw materials:

(2R,2'R)-bis[(S)-2-ethoxy-2-oxo-1-phenylethyl]-2,2'-([2-(diacetoxy)iodo-1,3-phenylene]bis(oxy))dipropanoate

(2R,2'R)-2,2'-((2-iodo-1,3-phenylene)bis(oxy))bis(N-mesitylpropanamide)

(2R,2'R)-2,2'-((2-iodo-1,3-phenylene)bis(oxy))bis(1-(piperidin-1-yl)propan-1-one)