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C12H16N2O

Base Information
  • Chemical Name:C12H16N2O
  • CAS No.:946390-36-9
  • Molecular Formula:C12H16N2O
  • Molecular Weight:204.272
  • Hs Code.:
C<sub>12</sub>H<sub>16</sub>N<sub>2</sub>O

Synonyms:C12H16N2O

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Chemical Property of C12H16N2O
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Technology Process of C12H16N2O

There total 1 articles about C12H16N2O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
(R)-2-amino-3-methylbutanol; phenyl isothiocyanate; In tetrahydrofuran; at 20 ℃;
With sodium hydroxide; p-toluenesulfonyl chloride; In tetrahydrofuran; water; at 20 ℃; Further stages.;
DOI:10.1016/j.tetlet.2007.05.073
Guidance literature:
With potassium tert-butylate; In tetrahydrofuran; at 20 ℃;
DOI:10.1016/j.tetlet.2007.05.073
Guidance literature:
Multi-step reaction with 2 steps
1: 75 percent / t-BuOK / tetrahydrofuran / 20 °C
2: 99 percent / LiHMDS / tetrahydrofuran / -78 °C
With potassium tert-butylate; lithium hexamethyldisilazane; In tetrahydrofuran;
DOI:10.1016/j.tetlet.2007.05.073
upstream raw materials:

(R)-2-amino-3-methylbutanol

phenyl isothiocyanate

Downstream raw materials:

C15H20N2O2

C22H25BrN2O2

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