2-bromo-7-(4-(N,N-bis(4-((2-ethylhexyl)oxy)phenyl)amino)phenyl)-9-oxo-9H-fluorene

Base Information

• Chemical Name: 2-bromo-7-(4-(N,N-bis(4-((2-ethylhexyl)oxy)phenyl)amino)phenyl)-9-oxo-9H-fluorene
• CAS No.: 1398122-55-8
• Molecular Formula: C₄₇H₅₂BrNO₃
• Molecular Weight: 758.839
• Mol file: 1398122-55-8.mol

Synonyms:2-bromo-7-(4-(N,N-bis(4-((2-ethylhexyl)oxy)phenyl)amino)phenyl)-9-oxo-9H-fluorene

Chemical Property of 2-bromo-7-(4-(N,N-bis(4-((2-ethylhexyl)oxy)phenyl)amino)phenyl)-9-oxo-9H-fluorene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-bromo-7-(4-(N,N-bis(4-((2-ethylhexyl)oxy)phenyl)amino)phenyl)-9-oxo-9H-fluorene

There total 2 articles about 2-bromo-7-(4-(N,N-bis(4-((2-ethylhexyl)oxy)phenyl)amino)phenyl)-9-oxo-9H-fluorene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.6%

2,7-dibromofluorene-9-one (14348-75-5) + 4-(2-ethylhexyloxy)-N-(4-(2-ethylhexyloxy)phenyl)-N-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)benzeneamine (1314556-70-1) → 2-bromo-7-(4-(N,N-bis(4-((2-ethylhexyl)oxy)phenyl)amino)phenyl)-9-oxo-9H-fluorene (1398122-55-8)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In toluene; for 24h; Reflux; Inert atmosphere;

DOI:10.1039/c2jm33105e

Reference yield:

4-bromo-N,N-bis((4-(2-ethyl)hexyloxy)phenyl)aniline (1192035-51-0) → 2-bromo-7-(4-(N,N-bis(4-((2-ethylhexyl)oxy)phenyl)amino)phenyl)-9-oxo-9H-fluorene (1398122-55-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 2.5 h / -78 °C / Inert atmosphere

1.2: -78 °C / Inert atmosphere

2.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate / toluene; water / 16 h / Inert atmosphere; Reflux

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; n-butyllithium; potassium carbonate; In tetrahydrofuran; hexane; water; toluene;

Reference yield: 75.0%

2-bromo-7-(4-(N,N-bis(4-((2-ethylhexyl)oxy)phenyl)amino)phenyl)-9-oxo-9H-fluorene (1398122-55-8) + (5-formylthiophen-2-yl)boronic acid → 5-(7-(4-(N,N-bis(4-((2-ethylhexyl)oxy)phenyl)amino)phenyl)-9-oxo-9H-fluoren-2-yl)thiophene-2-carbaldehyde (1398122-56-9)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In methanol; toluene; for 2h; Reflux; Inert atmosphere; Microwave irradiation;

DOI:10.1039/c2jm33105e

upstream raw materials:

2,7-dibromofluorene-9-one

4-(2-ethylhexyloxy)-N-(4-(2-ethylhexyloxy)phenyl)-N-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)benzeneamine

4-bromo-N,N-bis((4-(2-ethyl)hexyloxy)phenyl)aniline

Downstream raw materials:

5-(7-(4-(N,N-bis(4-((2-ethylhexyl)oxy)phenyl)amino)phenyl)-9-oxo-9H-fluoren-2-yl)thiophene-2-carbaldehyde

2-cyano-3-(5-(7-(4-(N,N-bis(4-((2-ethylhexyl)oxy)phenyl)amino)phenyl)-9-oxo-9H-fluoren-2-yl)thiophen-2-yl)acrylic acid

4-(7-(4-(N,N-bis(4-((2-ethylhexyl)oxy)phenyl)amino)phenyl)-9-oxo-9H-fluoren-2-yl)phenylcarbaldehyde

2-cyano-3-(4-(7-(4-(N,N-bis(4-((2-ethylhexyl)oxy)phenyl)amino)phenyl)-9-oxo-9H-fluoren-2-yl)phenyl)acrylic acid