4-((1R,2R)-2-{[(4-bromobenzyl)oxy]methyl}cyclopropyl)piperidine trifluoroacetate

Base Information

Chemical Name:4-((1R,2R)-2-{[(4-bromobenzyl)oxy]methyl}cyclopropyl)piperidine trifluoroacetate
CAS No.:1416366-21-6
Molecular Formula:C₂HF₃O₂*C₁₆H₂₂BrNO
Molecular Weight:438.285
Hs Code.:

Synonyms:4-((1R,2R)-2-{[(4-bromobenzyl)oxy]methyl}cyclopropyl)piperidine trifluoroacetate

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Chemical Property of 4-((1R,2R)-2-{[(4-bromobenzyl)oxy]methyl}cyclopropyl)piperidine trifluoroacetate

Chemical Property:

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Technology Process of 4-((1R,2R)-2-{[(4-bromobenzyl)oxy]methyl}cyclopropyl)piperidine trifluoroacetate

There total 1 articles about 4-((1R,2R)-2-{[(4-bromobenzyl)oxy]methyl}cyclopropyl)piperidine trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1416366-21-6
4-((1R,2R)-2-{[(4-bromobenzyl)oxy]methyl}cyclopropyl)piperidine trifluoroacetate

Guidance literature:

Reference yield:

: 506-68-3
bromocyane

: 1416366-21-6
4-((1R,2R)-2-{[(4-bromobenzyl)oxy]methyl}cyclopropyl)piperidine trifluoroacetate

: 1416366-22-7
4-((1R,2R)-2-{[(4-bromobenzyl)oxy]methyl}cyclopropyl)piperidine-1-carbonitrile

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In acetonitrile; at 20 ℃;

Reference yield:

: 1416366-21-6
4-((1R,2R)-2-{[(4-bromobenzyl)oxy]methyl}cyclopropyl)piperidine trifluoroacetate

: 1416364-34-5
1-(3-isopropyl-1,2,4-oxadiazol-5-y)l-4-[(1R,2R)-2-({[4-(methylsulfonyl)benzyl]oxy}methyl)cyclopropyl]piperidine

Guidance literature:: Multi-step reaction with 3 steps

1.1: N-ethyl-N,N-diisopropylamine / acetonitrile / 20 °C

2.1: N,N`-dimethylethylenediamine / copper(I) trifluoromethanesulfonate benzene complex / dimethyl sulfoxide / 120 °C / Inert atmosphere; Sealed vial

3.1: zinc(II) chloride / diethyl ether; tetrahydrofuran / 3 h / 20 °C

3.2: 1 h / 90 °C

With N-ethyl-N,N-diisopropylamine; zinc(II) chloride; N,N`-dimethylethylenediamine; copper(I) trifluoromethanesulfonate benzene complex; In tetrahydrofuran; diethyl ether; dimethyl sulfoxide; acetonitrile;