CYCLOHEXYL 2-METHOXYPHENYL KETONE

Base Information

• Chemical Name: CYCLOHEXYL 2-METHOXYPHENYL KETONE
• CAS No.: 111504-19-9
• Molecular Formula: C₁₄H₁₈O₂
• Molecular Weight: 218.296
• Mol file: 111504-19-9.mol

Synonyms:(E)-N′-(cyclohexyl(2-methoxyphenyl)methylene)-4-methylbenzenesulfonohydrazide

Chemical Property of CYCLOHEXYL 2-METHOXYPHENYL KETONE

Chemical Property:

• Vapor Pressure: 0.000162mmHg at 25°C

Purity/Quality:

98% ^*data from raw suppliers

Cyclohexyl2-methoxyphenylketone 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of CYCLOHEXYL 2-METHOXYPHENYL KETONE

There total 6 articles about CYCLOHEXYL 2-METHOXYPHENYL KETONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

N-(3,5-bis(trifluoromethyl)phenyl)-N-tosylcyclohexanecarboxamide + bydroxybis(2-methoxyphenyl)borane → (E)-N′-(cyclohexyl(2-methoxyphenyl)methylene)-4-methylbenzenesulfonohydrazide (111504-19-9)

Guidance literature:

With (bis(tricyclohexyl)phosphine)palladium(II) dichloride; potassium carbonate; tricyclohexylphosphine; In 1,4-dioxane; at 110 ℃; for 6h; Inert atmosphere; Schlenk technique;

DOI:10.1016/j.jorganchem.2015.07.009

Reference yield: 92.0%

methoxybenzene (100-66-3) + cyclohexanylcarbonyl chloride (2719-27-9) → cyclohexyl 4-methoxyphenyl ketone (7469-80-9) + cyclohexyl(3-methoxyphenyl)methanone (898792-05-7) + (E)-N′-(cyclohexyl(2-methoxyphenyl)methylene)-4-methylbenzenesulfonohydrazide (111504-19-9)

Guidance literature:

With rhenium(I) pentacarbonyl bromide; In 1,2-dichloro-ethane; for 2h; Heating;

DOI:10.1246/bcsj.68.2379

Reference yield: 62.0%

cyclohexane (110-82-7,25012-93-5) + ortho-anisaldehyde (135-02-4) → (E)-N′-(cyclohexyl(2-methoxyphenyl)methylene)-4-methylbenzenesulfonohydrazide (111504-19-9)

Guidance literature:

With di-tert-butyl peroxide; at 180 ℃; for 1h; Microwave irradiation; Inert atmosphere; Sealed tube;

DOI:10.1021/acs.joc.5b01824

upstream raw materials:

methoxybenzene

cyclohexanylcarbonyl chloride

Cyclohexanecarboxylic acid

cyclohexane

Downstream raw materials:

(E)-N′-(cyclohexyl(2-methoxyphenyl)methylene)-4-methylbenzenesulfonohydrazide