CYCLOHEXYL 3-METHOXYPHENYL KETONE

Base Information

• Chemical Name: CYCLOHEXYL 3-METHOXYPHENYL KETONE
• CAS No.: 898792-05-7
• Molecular Formula: C14H18O2
• Molecular Weight: 218.296
• Hs Code.: 2914509090
• Mol file: 898792-05-7.mol

Synonyms:CYCLOHEXYL 3-METHOXYPHENYL KETONE

Chemical Property of CYCLOHEXYL 3-METHOXYPHENYL KETONE

Chemical Property:

• Vapor Pressure: 0.00018mmHg at 25°C
• Boiling Point: 329.2°C at 760 mmHg
• Flash Point: 139.4°C
• PSA: 26.30000
• Density: 1.052g/cm³
• LogP: 3.45820

Purity/Quality:

97% ^*data from raw suppliers

Cyclohexyl3-methoxyphenylketone 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of CYCLOHEXYL 3-METHOXYPHENYL KETONE

There total 5 articles about CYCLOHEXYL 3-METHOXYPHENYL KETONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

methoxybenzene (100-66-3) + cyclohexanylcarbonyl chloride (2719-27-9) → cyclohexyl 4-methoxyphenyl ketone (7469-80-9) + cyclohexyl(3-methoxyphenyl)methanone (898792-05-7) + (E)-N′-(cyclohexyl(2-methoxyphenyl)methylene)-4-methylbenzenesulfonohydrazide (111504-19-9)

Guidance literature:

With rhenium(I) pentacarbonyl bromide; In 1,2-dichloro-ethane; for 2h; Heating;

DOI:10.1246/bcsj.68.2379

Reference yield: 63.0%

cyclohexane (110-82-7,25012-93-5) + m-anisoyl chloride (1711-05-3) → cyclohexyl(3-methoxyphenyl)methanone (898792-05-7)

Guidance literature:

With 2,6-dimethylpyridine; tetrakis(tetrabutylammonium)decatungstate(VI); 4,4'-di-tert-butyl-2,2'-bipyridine nickel(II) bromide; In acetonitrile; at 20 ℃; Inert atmosphere; Irradiation;

DOI:10.1002/anie.202108987

Reference yield: 61.0%

cyclohex-1-en-1-yl trifluoromethane sulfonate (28075-50-5) + 3-methoxy-benzaldehyde (591-31-1) → cyclohexyl(3-methoxyphenyl)methanone (898792-05-7)

Guidance literature:

With dicarbonylacetylacetonato rhodium (I); di-tert-butyl(methyl)phosphonium tetrafluoroborate salt; potassium formate; potassium carbonate; In 1,2-dimethoxyethane; at 130 ℃; for 16h; Inert atmosphere; Sealed tube;

DOI:10.1002/chem.201903668

upstream raw materials:

methoxybenzene

cyclohexanylcarbonyl chloride

cyclohexyl(3-methoxyphenyl)methanol

3-methoxy-1-iodobenzene

Downstream raw materials:

(S)-cyclohexyl(3-methoxyphenyl)methanol