CYCLOHEXYL 4-METHOXYPHENYL KETONE

Base Information

• Chemical Name: CYCLOHEXYL 4-METHOXYPHENYL KETONE
• CAS No.: 7469-80-9
• Molecular Formula: C14H18O2
• Molecular Weight: 218.296
• Hs Code.: 2914500090
• Mol file: 7469-80-9.mol

Synonyms:Ketone,cyclohexyl p-methoxyphenyl (7CI);Cyclohexyl 4-methoxyphenyl methanone;Cyclohexyl p-methoxyphenyl ketone;NSC 402217;p-Anisyl cyclohexyl ketone;

Chemical Property of CYCLOHEXYL 4-METHOXYPHENYL KETONE

Chemical Property:

• Vapor Pressure: 3.77E-05mmHg at 25°C
• Melting Point: 40-60 °C(Solv: ligroine (8032-32-4))
• Refractive Index: 1.529
• Boiling Point: 352.7 °C at 760 mmHg
• Flash Point: 155.5 °C
• PSA: 26.30000
• Density: 1.052 g/cm³
• LogP: 3.45820

Purity/Quality:

99% ^*data from raw suppliers

Cyclohexyl-(4-methoxyphenyl)methanone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Cyclohexyl-(4-methoxyphenyl)methanone is a useful chemical for research.

Technology Process of CYCLOHEXYL 4-METHOXYPHENYL KETONE

There total 54 articles about CYCLOHEXYL 4-METHOXYPHENYL KETONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

methoxybenzene (100-66-3) + cyclohexanylcarbonyl chloride (2719-27-9) → cyclohexyl 4-methoxyphenyl ketone (7469-80-9)

Guidance literature:

With indium; In 1,4-dioxane; for 4h; Heating;

DOI:10.1016/j.tetlet.2006.06.099

Reference yield: 98.0%

methoxybenzene (100-66-3) + Cyclohexanecarboxylic acid (98-89-5) → cyclohexyl 4-methoxyphenyl ketone (7469-80-9)

Guidance literature:

With methanesulfonic acid; pyrographite; at 80 ℃; for 0.0833333h;

DOI:10.1055/s-2004-831162

Reference yield: 88.0%

4-methoxy-benzoyl chloride (100-07-2) + cyclohexyltrifluoro-λ4-borane potassium salt (446065-11-8) → cyclohexyl 4-methoxyphenyl ketone (7469-80-9)

Guidance literature:

With potassium fluoride; (1,2-dimethoxyethane)dichloronickel(II); Ir(dF(CF₃)ppy)2(bpy)PF₆; 4,4'-di-tert-butyl-2,2'-bipyridine; In 1,2-dimethoxyethane; at 24 ℃; for 24h; Inert atmosphere; Sealed tube; Irradiation;

DOI:10.1021/acs.joc.6b02897

upstream raw materials:

methoxybenzene

cyclohexanylcarbonyl chloride

trimethylsilyl cyclohexanecarboxylate

Cyclohexanecarboxylic acid

Downstream raw materials:

1-cyclohexyl-1,2-bis-(4-methoxy-phenyl)-ethene

cyclohexyl-(4-methoxy-phenyl)-ketone-(2,4-dinitro-phenylhydrazone)